Home Immunology & Inflammation STING agonist E7766 diammonium salt For research use only.

E7766 diammonium salt

E7766 diammonium salt, a macrocycle-bridged STING agonist with a Kd of 40 nM, shows potent pan-genotypic and antitumor activities.

E7766 diammonium salt Chemical Structure

E7766 diammonium salt Chemical Structure

CAS No. 2242635-03-4

Purity & Quality Control

Batch: S961801 Water]45 mg/mL]false]]]false]]]false Purity: 99.87%
99.87

E7766 diammonium salt Related Products

Biological Activity

Description E7766 diammonium salt, a macrocycle-bridged STING agonist with a Kd of 40 nM, shows potent pan-genotypic and antitumor activities.
Targets
STING [1]
(in the isothermal titration calorimetry (ITC) assay)
40 nM(Kd)
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04144140 Terminated
Lymphoma|Advanced Solid Tumors
Eisai Inc.|H3 Biomedicine Inc.
 February 24 2020 Phase 1
NCT04109092 Withdrawn
Urinary Bladder Neoplasms
Eisai Inc.|H3 Biomedicine Inc.
 February 13 2020 Phase 1

Chemical Information & Solubility

Molecular Weight 780.66 Formula

C24H26F2N10O8P2S2.2H3N
CAS No. 2242635-03-4 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 45 mg/mL


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In vivo
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