Home Microbiology Topoisomerase inhibitor - Bacterial inhibitor - Antibiotics inhibitor - Antineoplastic and Immunosuppressive Antibiotics chemical Ciprofloxacin (CPX) hydrochloride For research use only.

Ciprofloxacin (CPX) hydrochloride

Synonyms: Bay-09867

Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).

Ciprofloxacin (CPX) hydrochloride Chemical Structure

Ciprofloxacin (CPX) hydrochloride Chemical Structure

CAS No. 93107-08-5

Purity & Quality Control

Batch: S500801 Water]30 mg/mL]false]DMSO]7 mg/mL]false]Ethanol]Insoluble]false Purity: 98%
98

Ciprofloxacin (CPX) hydrochloride Related Products

Signaling Pathway

Topoisomerase Signaling Pathways

Topoisomerase Signaling Pathway

Biological Activity

Description Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
Targets
DNA gyrase [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05828550 Not yet recruiting
Patients withInfections Caused by S.Aureus Like Skin Infections Chest Infections Surgical Site Infections and Urinary Tract Infections
Sohag University
 May 2023 Not Applicable

Chemical Information & Solubility

Molecular Weight 367.8 Formula

C17H19ClFN3O3
CAS No. 93107-08-5 SDF --
Smiles Cl.OC(=O)C1=CN(C2CC2)C3=CC(=C(F)C=C3C1=O)N4CCNCC4
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 30 mg/mL

DMSO : 7 mg/mL ( (19.03 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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