Home Metabolism Vitamin inhibitor Calcifediol monohydrate For research use only.

Calcifediol monohydrate

Synonyms: 25-hydroxy Vitamin D3 monohydrate

Calcifediol monohydrate(25-hydroxy Vitamin D3 monohydrate), is an effective vitamin D receptor (VDR) ligand and VD supplement. It acts as an inhibitor of vitamin D receptor (VDR) Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.

Calcifediol monohydrate Chemical Structure

Calcifediol monohydrate Chemical Structure

CAS No. 63283-36-3

Purity & Quality Control

Batch: E491301 DMSO]84 mg/mL]false]Ethanol]28 mg/mL]false]Water]Insoluble]false Purity: 98.76%
98.76

Calcifediol monohydrate Related Products

Biological Activity

Description Calcifediol monohydrate(25-hydroxy Vitamin D3 monohydrate), is an effective vitamin D receptor (VDR) ligand and VD supplement. It acts as an inhibitor of vitamin D receptor (VDR) Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.

Chemical Information & Solubility

Molecular Weight 418.65 Formula

C27H44O2.H2O
CAS No. 63283-36-3 SDF Download Calcifediol monohydrate SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 84 mg/mL ( (200.64 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 28 mg/mL

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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