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Brontictuzumab (Anti-NOTCH1)
Synonyms: OMP 52M51
Brontictuzumab (Anti-NOTCH1) is a monoclonal antibody that targets Notch1 signal. It inhibits tumor cell proliferation and can be used in the research of leukemia and lymphoma. MW :150 KD.
Purity & Quality Control
Choose Selective Notch Inhibitors
| Name | Citation | Notch | Others |
|---|---|---|---|
| RO4929097 | 116 | γ secretase,Aβ40 | |
| Semagacestat (LY450139) | 20 | Aβ42,Aβ38,Aβ40 | |
| DBZ (Dibenzazepine) | 38 | γ secretase | |
| LY411575 | 37 | γ secretase | |
| IMR-1A | 0 | ||
| IMR-1 | 7 | ||
| FLI-06 | 12 | ||
| Crenigacestat (LY3039478) | 24 | ||
| DAPT | Aβ | ||
| Limantrafin (CB-103) |
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Biological Activity
| Description | Brontictuzumab (Anti-NOTCH1) is a monoclonal antibody that targets Notch1 signal. It inhibits tumor cell proliferation and can be used in the research of leukemia and lymphoma. MW :150 KD. |
|---|
Product Details
| CAS No. | 1447814-75-6 |
|---|---|
| Molecular Weight | 150 |
| Isotype | Human IgG2SA |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100mMPro-Ac,20mMArg-Ac，pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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