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Elesclomol (STA-4783)

Name: Elesclomol (STA-4783)
Brand: Selleck Chemicals
SKU: S1052
Rating: 5 (107 reviews)

Catalog No.S1052 Purity:99.60%

Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.Elesclomol (STA-4783) is a potent copper ionophore and can be used in the research of copper-dependent cell death (cuproptosis).

Elesclomol (STA-4783) Chemical Structure

CAS No. 488832-69-5

Purity & Quality Control

Batch: Purity: 99.60%

99.60

Products often used together with Elesclomol (STA-4783)

Genipin

Elesclomol and Genipin significantly reduce mitochondrial membrane potential and induce apoptosis in A549 cells.

Lee JH, et al. Oncol Lett. 2020;20(6):374.

Elesclomol (STA-4783) Related Products

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Related Compound Libraries	Kinase Inhibitor Library Angiogenesis Related compound Library TGF-beta/Smad compound library Cytoskeletal Signaling Pathway Compound Library Anti-Cardiovascular Disease Compound Library	Click to Expand

Signaling Pathway

HSP (HSP90) Signaling Pathway

Cell Data

Cell Lines	Assay Type	Concentration	Activity Description	PMID
PC3 cells	Function assay		Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISA, IC50=0.113 μM	21341675
F-36P cells	Proliferation assay		Antiproliferative activity against human F-36P cells, IC50=0.28 μM	21341675
OCI-AML2 cells	Proliferation assay		Antiproliferative activity against human OCI-AML2 cells, IC50=0.35 μM	21341675
K562 cells	Proliferation assay		Antiproliferative activity against human K562 cells, IC50=18 μM	21341675
MES-SA	Cytotoxicity assay		Cytotoxicity against multidrug-resistant human MES-SA cells, IC50=0.005μM.	23937981
MES-SA/Dx5	Cytotoxicity assay		Cytotoxicity against human MES-SA/Dx5 cells, IC50=0.005μM.	23937981
Bowes	Cytotoxicity assay		Cytotoxicity against multidrug-resistant human Bowes cells, IC50=0.01μM.	23937981
DU145	Cytotoxicity assay		Cytotoxicity against human DU145 cells, IC50=0.02μM.	23937981
Ramos	Function assay		Induction of Hsp70 production in human Ramos cells after 5 hrs by ELISA, EC50=0.02μM.	23937981
HL60	Cytotoxicity assay		Cytotoxicity against multidrug-resistant human HL60 cells, IC50=0.05μM.	23937981
MES-SA	Cytotoxicity assay		Cytotoxicity against human MES-SA cells, IC50=0.05μM.	23937981
MIP101	Cytotoxicity assay		Cytotoxicity against human MIP101 cells, IC50=0.05μM.	23937981
A549	Cytotoxicity assay		Cytotoxicity against human A549 cells, IC50=0.1μM.	23937981
Clone A	Cytotoxicity assay		Cytotoxicity against human Clone A cells, IC50=0.1μM.	23937981
Bowes	Cytotoxicity assay		Cytotoxicity against wild type human Bowes cells, IC50=0.2μM.	23937981
HL60	Cytotoxicity assay		Cytotoxicity against human HL60 cells, IC50=0.4μM.	23937981
MDA435	Cytotoxicity assay		Cytotoxicity against human MDA435 cells, IC50=5μM.	23937981
MDA-MB-435	Antitumor assay	25 mg/kg	Antitumor activity against human MDA-MB-435 cells xenografted in CD-1 nu/nu mouse assessed as tumor regression at 25 mg/kg, iv qod administered 3 times a week for 2 consecutive weeks	23937981
NOS-1	Growth inhibition assay		Inhibition of human NOS-1 cell growth in a cell viability assay, IC50=0.0000366μM.	SANGER
CAL-51	Growth inhibition assay		Inhibition of human CAL-51 cell growth in a cell viability assay, IC50=0.0001264μM.	SANGER
ABC-1	Growth inhibition assay		Inhibition of human ABC-1 cell growth in a cell viability assay, IC50=0.0003653μM.	SANGER
A2780	Growth inhibition assay		Inhibition of human A2780 cell growth in a cell viability assay, IC50=0.0005939μM.	SANGER
ES1	Growth inhibition assay		Inhibition of human ES1 cell growth in a cell viability assay, IC50=0.0007491μM.	SANGER
HUTU-80	Growth inhibition assay		Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50=0.0007911μM.	SANGER
NCI-H292	Growth inhibition assay		Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50=0.0008859μM.	SANGER
NB69	Growth inhibition assay		Inhibition of human NB69 cell growth in a cell viability assay, IC50=0.001218μM.	SANGER
ES8	Growth inhibition assay		Inhibition of human ES8 cell growth in a cell viability assay, IC50=0.001317μM.	SANGER
BCPAP	Growth inhibition assay		Inhibition of human BCPAP cell growth in a cell viability assay, IC50=0.001345μM.	SANGER
T-24	Growth inhibition assay		Inhibition of human T-24 cell growth in a cell viability assay, IC50=0.001551μM.	SANGER
EW-16	Growth inhibition assay		Inhibition of human EW-16 cell growth in a cell viability assay, IC50=0.001609μM.	SANGER
OVCAR-5	Growth inhibition assay		Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50=0.001835μM.	SANGER
SF126	Growth inhibition assay		Inhibition of human SF126 cell growth in a cell viability assay, IC50=0.001954μM.	SANGER
KP-4	Growth inhibition assay		Inhibition of human KP-4 cell growth in a cell viability assay, IC50=0.002173μM.	SANGER
GAMG	Growth inhibition assay		Inhibition of human GAMG cell growth in a cell viability assay, IC50=0.00251μM.	SANGER
HOS	Growth inhibition assay		Inhibition of human HOS cell growth in a cell viability assay, IC50=0.002531μM.	SANGER
CHL-1	Growth inhibition assay		Inhibition of human CHL-1 cell growth in a cell viability assay, IC50=0.002811μM.	SANGER
AGS	Growth inhibition assay		Inhibition of human AGS cell growth in a cell viability assay, IC50=0.002863μM.	SANGER
MDA-MB-157	Growth inhibition assay		Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50=0.002918μM.	SANGER
HSC-3	Growth inhibition assay		Inhibition of human HSC-3 cell growth in a cell viability assay, IC50=0.003015μM.	SANGER
CAL-72	Growth inhibition assay		Inhibition of human CAL-72 cell growth in a cell viability assay, IC50=0.003023μM.	SANGER
NBsusSR	Growth inhibition assay		Inhibition of human NBsusSR cell growth in a cell viability assay, IC50=0.003134μM.	SANGER
ES7	Growth inhibition assay		Inhibition of human ES7 cell growth in a cell viability assay, IC50=0.003592μM.	SANGER
H-EMC-SS	Growth inhibition assay		Inhibition of human H-EMC-SS cell growth in a cell viability assay, IC50=0.003684μM.	SANGER
NCI-H1703	Growth inhibition assay		Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50=0.003685μM.	SANGER
BHT-101	Growth inhibition assay		Inhibition of human BHT-101 cell growth in a cell viability assay, IC50=0.00372μM.	SANGER
SK-OV-3	Growth inhibition assay		Inhibition of human SK-OV-3 cell growth in a cell viability assay, IC50=0.003751μM.	SANGER
EW-24	Growth inhibition assay		Inhibition of human EW-24 cell growth in a cell viability assay, IC50=0.003835μM.	SANGER
PSN1	Growth inhibition assay		Inhibition of human PSN1 cell growth in a cell viability assay, IC50=0.003841μM.	SANGER
OVCAR-8	Growth inhibition assay		Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50=0.003995μM.	SANGER
P12-ICHIKAWA	Growth inhibition assay		Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50=0.004044μM.	SANGER
SW756	Growth inhibition assay		Inhibition of human SW756 cell growth in a cell viability assay, IC50=0.004131μM.	SANGER
NCI-H1563	Growth inhibition assay		Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50=0.004133μM.	SANGER
A375	Growth inhibition assay		Inhibition of human A375 cell growth in a cell viability assay, IC50=0.004143μM.	SANGER
Ca9-22	Growth inhibition assay		Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50=0.004247μM.	SANGER
SW1990	Growth inhibition assay		Inhibition of human SW1990 cell growth in a cell viability assay, IC50=0.004318μM.	SANGER
ES4	Growth inhibition assay		Inhibition of human ES4 cell growth in a cell viability assay, IC50=0.004391μM.	SANGER
HCE-T	Growth inhibition assay		Inhibition of human HCE-T cell growth in a cell viability assay, IC50=0.004451μM.	SANGER
MOLT-16	Growth inhibition assay		Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50=0.004527μM.	SANGER
HSC-4	Growth inhibition assay		Inhibition of human HSC-4 cell growth in a cell viability assay, IC50=0.004803μM.	SANGER
NCI-SNU-1	Growth inhibition assay		Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50=0.004862μM.	SANGER
EW-11	Growth inhibition assay		Inhibition of human EW-11 cell growth in a cell viability assay, IC50=0.004896μM.	SANGER
HT-1080	Growth inhibition assay		Inhibition of human HT-1080 cell growth in a cell viability assay, IC50=0.004993μM.	SANGER
SW1710	Growth inhibition assay		Inhibition of human SW1710 cell growth in a cell viability assay, IC50=0.005164μM.	SANGER
EW-1	Growth inhibition assay		Inhibition of human EW-1 cell growth in a cell viability assay, IC50=0.005237μM.	SANGER
BV-173	Growth inhibition assay		Inhibition of human BV-173 cell growth in a cell viability assay, IC50=0.005387μM.	SANGER
ChaGo-K-1	Growth inhibition assay		Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50=0.0054μM.	SANGER
TE-8	Growth inhibition assay		Inhibition of human TE-8 cell growth in a cell viability assay, IC50=0.005405μM.	SANGER
G-401	Growth inhibition assay		Inhibition of human G-401 cell growth in a cell viability assay, IC50=0.005426μM.	SANGER
KOSC-2	Growth inhibition assay		Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50=0.005453μM.	SANGER
HuCCT1	Growth inhibition assay		Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50=0.00552μM.	SANGER
FADU	Growth inhibition assay		Inhibition of human FADU cell growth in a cell viability assay, IC50=0.005663μM.	SANGER
MHH-ES-1	Growth inhibition assay		Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50=0.005692μM.	SANGER
ES3	Growth inhibition assay		Inhibition of human ES3 cell growth in a cell viability assay, IC50=0.005793μM.	SANGER
OVCAR-4	Growth inhibition assay		Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50=0.00587μM.	SANGER
HD-MY-Z	Growth inhibition assay		Inhibition of human HD-MY-Z cell growth in a cell viability assay, IC50=0.005909μM.	SANGER
JAR	Growth inhibition assay		Inhibition of human JAR cell growth in a cell viability assay, IC50=0.005967μM.	SANGER
A427	Growth inhibition assay		Inhibition of human A427 cell growth in a cell viability assay, IC50=0.006067μM.	SANGER
697	Growth inhibition assay		Inhibition of human 697 cell growth in a cell viability assay, IC50=0.006126μM.	SANGER
OVCAR-3	Growth inhibition assay		Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50=0.006201μM.	SANGER
NB14	Growth inhibition assay		Inhibition of human NB14 cell growth in a cell viability assay, IC50=0.006637μM.	SANGER
GB-1	Growth inhibition assay		Inhibition of human GB-1 cell growth in a cell viability assay, IC50=0.006709μM.	SANGER
COR-L105	Growth inhibition assay		Inhibition of human COR-L105 cell growth in a cell viability assay, IC50=0.006764μM.	SANGER
647-V	Growth inhibition assay		Inhibition of human 647-V cell growth in a cell viability assay, IC50=0.006905μM.	SANGER
K5	Growth inhibition assay		Inhibition of human K5 cell growth in a cell viability assay, IC50=0.006999μM.	SANGER
DMS-273	Growth inhibition assay		Inhibition of human DMS-273 cell growth in a cell viability assay, IC50=0.007057μM.	SANGER
UM-UC-3	Growth inhibition assay		Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50=0.007063μM.	SANGER
HEL	Growth inhibition assay		Inhibition of human HEL cell growth in a cell viability assay, IC50=0.007077μM.	SANGER
KU-19-19	Growth inhibition assay		Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50=0.007094μM.	SANGER
MC-IXC	Growth inhibition assay		Inhibition of human MC-IXC cell growth in a cell viability assay, IC50=0.007171μM.	SANGER
H4	Growth inhibition assay		Inhibition of human H4 cell growth in a cell viability assay, IC50=0.00725μM.	SANGER
NUGC-3	Growth inhibition assay		Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50=0.007328μM.	SANGER
CHP-212	Growth inhibition assay		Inhibition of human CHP-212 cell growth in a cell viability assay, IC50=0.007342μM.	SANGER
SW982	Growth inhibition assay		Inhibition of human SW982 cell growth in a cell viability assay, IC50=0.00744μM.	SANGER
C-33-A	Growth inhibition assay		Inhibition of human C-33-A cell growth in a cell viability assay, IC50=0.007579μM.	SANGER
HGC-27	Growth inhibition assay		Inhibition of human HGC-27 cell growth in a cell viability assay, IC50=0.007592μM.	SANGER
VA-ES-BJ	Growth inhibition assay		Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50=0.007641μM.	SANGER
SW13	Growth inhibition assay		Inhibition of human SW13 cell growth in a cell viability assay, IC50=0.007689μM.	SANGER
EFO-27	Growth inhibition assay		Inhibition of human EFO-27 cell growth in a cell viability assay, IC50=0.007718μM.	SANGER
LNCaP-Clone-FGC	Growth inhibition assay		Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50=0.007726μM.	SANGER
PC-3	Growth inhibition assay		Inhibition of human PC-3 cell growth in a cell viability assay, IC50=0.007885μM.	SANGER
HEC-1	Growth inhibition assay		Inhibition of human HEC-1 cell growth in a cell viability assay, IC50=0.008254μM.	SANGER
GI-1	Growth inhibition assay		Inhibition of human GI-1 cell growth in a cell viability assay, IC50=0.008261μM.	SANGER
EGI-1	Growth inhibition assay		Inhibition of human EGI-1 cell growth in a cell viability assay, IC50=0.008376μM.	SANGER
HCC1395	Growth inhibition assay		Inhibition of human HCC1395 cell growth in a cell viability assay, IC50=0.008469μM.	SANGER
RERF-LC-MS	Growth inhibition assay		Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50=0.008579μM.	SANGER
CP50-MEL-B	Growth inhibition assay		Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50=0.008626μM.	SANGER
CTB-1	Growth inhibition assay		Inhibition of human CTB-1 cell growth in a cell viability assay, IC50=0.00864μM.	SANGER
JEG-3	Growth inhibition assay		Inhibition of human JEG-3 cell growth in a cell viability assay, IC50=0.00884μM.	SANGER
PA-1	Growth inhibition assay		Inhibition of human PA-1 cell growth in a cell viability assay, IC50=0.008844μM.	SANGER
A204	Growth inhibition assay		Inhibition of human A204 cell growth in a cell viability assay, IC50=0.008848μM.	SANGER
NCI-H1355	Growth inhibition assay		Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50=0.008886μM.	SANGER
NB17	Growth inhibition assay		Inhibition of human NB17 cell growth in a cell viability assay, IC50=0.008939μM.	SANGER
SK-PN-DW	Growth inhibition assay		Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50=0.009023μM.	SANGER
NCI-H1693	Growth inhibition assay		Inhibition of human NCI-H1693 cell growth in a cell viability assay, IC50=0.009094μM.	SANGER
MPP-89	Growth inhibition assay		Inhibition of human MPP-89 cell growth in a cell viability assay, IC50=0.009133μM.	SANGER
8-MG-BA	Growth inhibition assay		Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50=0.00914μM.	SANGER
SF295	Growth inhibition assay		Inhibition of human SF295 cell growth in a cell viability assay, IC50=0.009195μM.	SANGER
COLO-684	Growth inhibition assay		Inhibition of human COLO-684 cell growth in a cell viability assay, IC50=0.009208μM.	SANGER
DMS-114	Growth inhibition assay		Inhibition of human DMS-114 cell growth in a cell viability assay, IC50=0.009431μM.	SANGER
SNU-387	Growth inhibition assay		Inhibition of human SNU-387 cell growth in a cell viability assay, IC50=0.00949μM.	SANGER
KNS-62	Growth inhibition assay		Inhibition of human KNS-62 cell growth in a cell viability assay, IC50=0.009619μM.	SANGER
PANC-08-13	Growth inhibition assay		Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50=0.009634μM.	SANGER
DBTRG-05MG	Growth inhibition assay		Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50=0.009769μM.	SANGER
769-P	Growth inhibition assay		Inhibition of human 769-P cell growth in a cell viability assay, IC50=0.009821μM.	SANGER
U251	Growth inhibition assay		Inhibition of human U251 cell growth in a cell viability assay, IC50=0.009856μM.	SANGER
HLE	Growth inhibition assay		Inhibition of human HLE cell growth in a cell viability assay, IC50=0.009925μM.	SANGER
ONS-76	Growth inhibition assay		Inhibition of human ONS-76 cell growth in a cell viability assay, IC50=0.01026μM.	SANGER
SK-LU-1	Growth inhibition assay		Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50=0.01034μM.	SANGER
8505C	Growth inhibition assay		Inhibition of human 8505C cell growth in a cell viability assay, IC50=0.01053μM.	SANGER
MEL-JUSO	Growth inhibition assay		Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50=0.01064μM.	SANGER
SW1573	Growth inhibition assay		Inhibition of human SW1573 cell growth in a cell viability assay, IC50=0.01068μM.	SANGER
LB1047-RCC	Growth inhibition assay		Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50=0.01075μM.	SANGER
AN3-CA	Growth inhibition assay		Inhibition of human AN3-CA cell growth in a cell viability assay, IC50=0.01079μM.	SANGER
CGTH-W-1	Growth inhibition assay		Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50=0.01095μM.	SANGER
Saos-2	Growth inhibition assay		Inhibition of human Saos-2 cell growth in a cell viability assay, IC50=0.01108μM.	SANGER
22RV1	Growth inhibition assay		Inhibition of human 22RV1 cell growth in a cell viability assay, IC50=0.0113μM.	SANGER
IST-MEL1	Growth inhibition assay		Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50=0.01134μM.	SANGER
A101D	Growth inhibition assay		Inhibition of human A101D cell growth in a cell viability assay, IC50=0.01142μM.	SANGER
MHH-PREB-1	Growth inhibition assay		Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50=0.01145μM.	SANGER
NEC8	Growth inhibition assay		Inhibition of human NEC8 cell growth in a cell viability assay, IC50=0.01149μM.	SANGER
A673	Growth inhibition assay		Inhibition of human A673 cell growth in a cell viability assay, IC50=0.0116μM.	SANGER
ACN	Growth inhibition assay		Inhibition of human ACN cell growth in a cell viability assay, IC50=0.01172μM.	SANGER
ES5	Growth inhibition assay		Inhibition of human ES5 cell growth in a cell viability assay, IC50=0.0118μM.	SANGER
Ramos-2G6-4C10	Growth inhibition assay		Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50=0.01199μM.	SANGER
D-423MG	Growth inhibition assay		Inhibition of human D-423MG cell growth in a cell viability assay, IC50=0.01199μM.	SANGER
NCI-H23	Growth inhibition assay		Inhibition of human NCI-H23 cell growth in a cell viability assay, IC50=0.01222μM.	SANGER
L-363	Growth inhibition assay		Inhibition of human L-363 cell growth in a cell viability assay, IC50=0.01227μM.	SANGER
SJSA-1	Growth inhibition assay		Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50=0.01233μM.	SANGER
NCI-H510A	Growth inhibition assay		Inhibition of human NCI-H510A cell growth in a cell viability assay, IC50=0.01239μM.	SANGER
TYK-nu	Growth inhibition assay		Inhibition of human TYK-nu cell growth in a cell viability assay, IC50=0.01239μM.	SANGER
NCI-H661	Growth inhibition assay		Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50=0.01247μM.	SANGER
YKG-1	Growth inhibition assay		Inhibition of human YKG-1 cell growth in a cell viability assay, IC50=0.01256μM.	SANGER
VM-CUB-1	Growth inhibition assay		Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50=0.01267μM.	SANGER
PFSK-1	Growth inhibition assay		Inhibition of human PFSK-1 cell growth in a cell viability assay, IC50=0.01268μM.	SANGER
MZ7-mel	Growth inhibition assay		Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50=0.01271μM.	SANGER
HOP-92	Growth inhibition assay		Inhibition of human HOP-92 cell growth in a cell viability assay, IC50=0.01272μM.	SANGER
SF268	Growth inhibition assay		Inhibition of human SF268 cell growth in a cell viability assay, IC50=0.01286μM.	SANGER
786-0	Growth inhibition assay		Inhibition of human 786-0 cell growth in a cell viability assay, IC50=0.01287μM.	SANGER
TGBC24TKB	Growth inhibition assay		Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50=0.01292μM.	SANGER
HT-144	Growth inhibition assay		Inhibition of human HT-144 cell growth in a cell viability assay, IC50=0.01303μM.	SANGER
RD	Growth inhibition assay		Inhibition of human RD cell growth in a cell viability assay, IC50=0.01311μM.	SANGER
CAL-39	Growth inhibition assay		Inhibition of human CAL-39 cell growth in a cell viability assay, IC50=0.01329μM.	SANGER
NCI-H1755	Growth inhibition assay		Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50=0.01333μM.	SANGER
U031	Growth inhibition assay		Inhibition of human U031 cell growth in a cell viability assay, IC50=0.01342μM.	SANGER
RXF393	Growth inhibition assay		Inhibition of human RXF393 cell growth in a cell viability assay, IC50=0.01344μM.	SANGER
TCCSUP	Growth inhibition assay		Inhibition of human TCCSUP cell growth in a cell viability assay, IC50=0.01346μM.	SANGER
MLMA	Growth inhibition assay		Inhibition of human MLMA cell growth in a cell viability assay, IC50=0.01358μM.	SANGER
NCI-H1395	Growth inhibition assay		Inhibition of human NCI-H1395 cell growth in a cell viability assay, IC50=0.01358μM.	SANGER
NCI-H358	Growth inhibition assay		Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50=0.01365μM.	SANGER
NCI-H28	Growth inhibition assay		Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50=0.01369μM.	SANGER
KS-1	Growth inhibition assay		Inhibition of human KS-1 cell growth in a cell viability assay, IC50=0.01378μM.	SANGER
A2058	Growth inhibition assay		Inhibition of human A2058 cell growth in a cell viability assay, IC50=0.01385μM.	SANGER
CAL-120	Growth inhibition assay		Inhibition of human CAL-120 cell growth in a cell viability assay, IC50=0.01395μM.	SANGER
MKN28	Growth inhibition assay		Inhibition of human MKN28 cell growth in a cell viability assay, IC50=0.01398μM.	SANGER
LXF-289	Growth inhibition assay		Inhibition of human LXF-289 cell growth in a cell viability assay, IC50=0.01404μM.	SANGER
SK-UT-1	Growth inhibition assay		Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50=0.01409μM.	SANGER
J82	Growth inhibition assay		Inhibition of human J82 cell growth in a cell viability assay, IC50=0.01413μM.	SANGER
COLO-679	Growth inhibition assay		Inhibition of human COLO-679 cell growth in a cell viability assay, IC50=0.01414μM.	SANGER
SNU-449	Growth inhibition assay		Inhibition of human SNU-449 cell growth in a cell viability assay, IC50=0.01419μM.	SANGER
SW954	Growth inhibition assay		Inhibition of human SW954 cell growth in a cell viability assay, IC50=0.01421μM.	SANGER
RT-112	Growth inhibition assay		Inhibition of human RT-112 cell growth in a cell viability assay, IC50=0.01423μM.	SANGER
MN-60	Growth inhibition assay		Inhibition of human MN-60 cell growth in a cell viability assay, IC50=0.01428μM.	SANGER
J-RT3-T3-5	Growth inhibition assay		Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50=0.01439μM.	SANGER
NB7	Growth inhibition assay		Inhibition of human NB7 cell growth in a cell viability assay, IC50=0.01439μM.	SANGER
LB373-MEL-D	Growth inhibition assay		Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50=0.01467μM.	SANGER
TE-5	Growth inhibition assay		Inhibition of human TE-5 cell growth in a cell viability assay, IC50=0.01504μM.	SANGER
SNU-423	Growth inhibition assay		Inhibition of human SNU-423 cell growth in a cell viability assay, IC50=0.01515μM.	SANGER
NB10	Growth inhibition assay		Inhibition of human NB10 cell growth in a cell viability assay, IC50=0.01517μM.	SANGER
TI-73	Growth inhibition assay		Inhibition of human TI-73 cell growth in a cell viability assay, IC50=0.01522μM.	SANGER
D-566MG	Growth inhibition assay		Inhibition of human D-566MG cell growth in a cell viability assay, IC50=0.01523μM.	SANGER
HN	Growth inhibition assay		Inhibition of human HN cell growth in a cell viability assay, IC50=0.01538μM.	SANGER
Hs-578-T	Growth inhibition assay		Inhibition of human Hs-578-T cell growth in a cell viability assay, IC50=0.01554μM.	SANGER
U-266	Growth inhibition assay		Inhibition of human U-266 cell growth in a cell viability assay, IC50=0.01582μM.	SANGER
BT-549	Growth inhibition assay		Inhibition of human BT-549 cell growth in a cell viability assay, IC50=0.01583μM.	SANGER
GT3TKB	Growth inhibition assay		Inhibition of human GT3TKB cell growth in a cell viability assay, IC50=0.016μM.	SANGER
G-402	Growth inhibition assay		Inhibition of human G-402 cell growth in a cell viability assay, IC50=0.01617μM.	SANGER
ME-180	Growth inhibition assay		Inhibition of human ME-180 cell growth in a cell viability assay, IC50=0.01624μM.	SANGER
NCI-H2126	Growth inhibition assay		Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50=0.01631μM.	SANGER
639-V	Growth inhibition assay		Inhibition of human 639-V cell growth in a cell viability assay, IC50=0.01674μM.	SANGER
T47D	Growth inhibition assay		Inhibition of human T47D cell growth in a cell viability assay, IC50=0.01679μM.	SANGER
Daoy	Growth inhibition assay		Inhibition of human Daoy cell growth in a cell viability assay, IC50=0.0168μM.	SANGER
DK-MG	Growth inhibition assay		Inhibition of human DK-MG cell growth in a cell viability assay, IC50=0.01706μM.	SANGER
MIA-PaCa-2	Growth inhibition assay		Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50=0.01711μM.	SANGER
KNS-81-FD	Growth inhibition assay		Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50=0.01746μM.	SANGER
HuH-7	Growth inhibition assay		Inhibition of human HuH-7 cell growth in a cell viability assay, IC50=0.01764μM.	SANGER
DOK	Growth inhibition assay		Inhibition of human DOK cell growth in a cell viability assay, IC50=0.01792μM.	SANGER
MV-4-11	Growth inhibition assay		Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50=0.018μM.	SANGER
NCI-H1048	Growth inhibition assay		Inhibition of human NCI-H1048 cell growth in a cell viability assay, IC50=0.01835μM.	SANGER
NCI-H1299	Growth inhibition assay		Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50=0.01854μM.	SANGER
GOTO	Growth inhibition assay		Inhibition of human GOTO cell growth in a cell viability assay, IC50=0.01865μM.	SANGER
MDA-MB-231	Growth inhibition assay		Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50=0.01904μM.	SANGER
BT-474	Growth inhibition assay		Inhibition of human BT-474 cell growth in a cell viability assay, IC50=0.01921μM.	SANGER
DEL	Growth inhibition assay		Inhibition of human DEL cell growth in a cell viability assay, IC50=0.01922μM.	SANGER
NTERA-S-cl-D1	Growth inhibition assay		Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50=0.01939μM.	SANGER
HCC1419	Growth inhibition assay		Inhibition of human HCC1419 cell growth in a cell viability assay, IC50=0.01959μM.	SANGER
A549	Growth inhibition assay		Inhibition of human A549 cell growth in a cell viability assay, IC50=0.0196μM.	SANGER
LK-2	Growth inhibition assay		Inhibition of human LK-2 cell growth in a cell viability assay, IC50=0.01969μM.	SANGER
KYSE-410	Growth inhibition assay		Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50=0.0197μM.	SANGER
U-2-OS	Growth inhibition assay		Inhibition of human U-2-OS cell growth in a cell viability assay, IC50=0.01973μM.	SANGER
EW-13	Growth inhibition assay		Inhibition of human EW-13 cell growth in a cell viability assay, IC50=0.01975μM.	SANGER
NMC-G1	Growth inhibition assay		Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50=0.02039μM.	SANGER
BFTC-905	Growth inhibition assay		Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50=0.02046μM.	SANGER
M059J	Growth inhibition assay		Inhibition of human M059J cell growth in a cell viability assay, IC50=0.02055μM.	SANGER
HuP-T4	Growth inhibition assay		Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50=0.02073μM.	SANGER
A172	Growth inhibition assay		Inhibition of human A172 cell growth in a cell viability assay, IC50=0.02089μM.	SANGER
RKO	Growth inhibition assay		Inhibition of human RKO cell growth in a cell viability assay, IC50=0.02098μM.	SANGER
KYSE-140	Growth inhibition assay		Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50=0.02099μM.	SANGER
HuO9	Growth inhibition assay		Inhibition of human HuO9 cell growth in a cell viability assay, IC50=0.02154μM.	SANGER
SBC-5	Growth inhibition assay		Inhibition of human SBC-5 cell growth in a cell viability assay, IC50=0.02162μM.	SANGER
NCI-H2452	Growth inhibition assay		Inhibition of human NCI-H2452 cell growth in a cell viability assay, IC50=0.02172μM.	SANGER
HT-1197	Growth inhibition assay		Inhibition of human HT-1197 cell growth in a cell viability assay, IC50=0.02182μM.	SANGER
UACC-257	Growth inhibition assay		Inhibition of human UACC-257 cell growth in a cell viability assay, IC50=0.02197μM.	SANGER
CAL-33	Growth inhibition assay		Inhibition of human CAL-33 cell growth in a cell viability assay, IC50=0.02223μM.	SANGER
Becker	Growth inhibition assay		Inhibition of human Becker cell growth in a cell viability assay, IC50=0.02227μM.	SANGER
SAS	Growth inhibition assay		Inhibition of human SAS cell growth in a cell viability assay, IC50=0.0225μM.	SANGER
SCC-25	Growth inhibition assay		Inhibition of human SCC-25 cell growth in a cell viability assay, IC50=0.02296μM.	SANGER
NB13	Growth inhibition assay		Inhibition of human NB13 cell growth in a cell viability assay, IC50=0.02311μM.	SANGER
UACC-62	Growth inhibition assay		Inhibition of human UACC-62 cell growth in a cell viability assay, IC50=0.02319μM.	SANGER
no-11	Growth inhibition assay		Inhibition of human no-11 cell growth in a cell viability assay, IC50=0.02328μM.	SANGER
DSH1	Growth inhibition assay		Inhibition of human DSH1 cell growth in a cell viability assay, IC50=0.02332μM.	SANGER
GCT	Growth inhibition assay		Inhibition of human GCT cell growth in a cell viability assay, IC50=0.02339μM.	SANGER
D-336MG	Growth inhibition assay		Inhibition of human D-336MG cell growth in a cell viability assay, IC50=0.02343μM.	SANGER
HCC1806	Growth inhibition assay		Inhibition of human HCC1806 cell growth in a cell viability assay, IC50=0.02348μM.	SANGER
KYSE-180	Growth inhibition assay		Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50=0.02384μM.	SANGER
HuO-3N1	Growth inhibition assay		Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50=0.02396μM.	SANGER
CAKI-1	Growth inhibition assay		Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50=0.02412μM.	SANGER
YH-13	Growth inhibition assay		Inhibition of human YH-13 cell growth in a cell viability assay, IC50=0.02415μM.	SANGER
BB65-RCC	Growth inhibition assay		Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50=0.02416μM.	SANGER
SF539	Growth inhibition assay		Inhibition of human SF539 cell growth in a cell viability assay, IC50=0.02437μM.	SANGER
HO-1-N-1	Growth inhibition assay		Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50=0.0245μM.	SANGER
NCI-H1581	Growth inhibition assay		Inhibition of human NCI-H1581 cell growth in a cell viability assay, IC50=0.02462μM.	SANGER
PC-14	Growth inhibition assay		Inhibition of human PC-14 cell growth in a cell viability assay, IC50=0.02473μM.	SANGER
D-247MG	Growth inhibition assay		Inhibition of human D-247MG cell growth in a cell viability assay, IC50=0.02473μM.	SANGER
23132-87	Growth inhibition assay		Inhibition of human 23132-87 cell growth in a cell viability assay, IC50=0.02492μM.	SANGER
SCC-15	Growth inhibition assay		Inhibition of human SCC-15 cell growth in a cell viability assay, IC50=0.02563μM.	SANGER
D-502MG	Growth inhibition assay		Inhibition of human D-502MG cell growth in a cell viability assay, IC50=0.02581μM.	SANGER
MDA-MB-361	Growth inhibition assay		Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50=0.02589μM.	SANGER
MKN1	Growth inhibition assay		Inhibition of human MKN1 cell growth in a cell viability assay, IC50=0.02597μM.	SANGER
RO82-W-1	Growth inhibition assay		Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50=0.02622μM.	SANGER
Mewo	Growth inhibition assay		Inhibition of human Mewo cell growth in a cell viability assay, IC50=0.02629μM.	SANGER
C32	Growth inhibition assay		Inhibition of human C32 cell growth in a cell viability assay, IC50=0.0263μM.	SANGER
NCI-H2030	Growth inhibition assay		Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50=0.02636μM.	SANGER
FTC-133	Growth inhibition assay		Inhibition of human FTC-133 cell growth in a cell viability assay, IC50=0.02701μM.	SANGER
S-117	Growth inhibition assay		Inhibition of human S-117 cell growth in a cell viability assay, IC50=0.02741μM.	SANGER
A704	Growth inhibition assay		Inhibition of human A704 cell growth in a cell viability assay, IC50=0.02745μM.	SANGER
G-361	Growth inhibition assay		Inhibition of human G-361 cell growth in a cell viability assay, IC50=0.02754μM.	SANGER
LB831-BLC	Growth inhibition assay		Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50=0.02772μM.	SANGER
LC-2-ad	Growth inhibition assay		Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50=0.02781μM.	SANGER
SN12C	Growth inhibition assay		Inhibition of human SN12C cell growth in a cell viability assay, IC50=0.02843μM.	SANGER
MKN45	Growth inhibition assay		Inhibition of human MKN45 cell growth in a cell viability assay, IC50=0.02868μM.	SANGER
NCI-H2347	Growth inhibition assay		Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50=0.02874μM.	SANGER
COLO-792	Growth inhibition assay		Inhibition of human COLO-792 cell growth in a cell viability assay, IC50=0.02877μM.	SANGER
NCI-H2170	Growth inhibition assay		Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50=0.02885μM.	SANGER
EPLC-272H	Growth inhibition assay		Inhibition of human EPLC-272H cell growth in a cell viability assay, IC50=0.02913μM.	SANGER
COLO-800	Growth inhibition assay		Inhibition of human COLO-800 cell growth in a cell viability assay, IC50=0.02992μM.	SANGER
RPMI-8866	Growth inhibition assay		Inhibition of human RPMI-8866 cell growth in a cell viability assay, IC50=0.03002μM.	SANGER
SK-N-AS	Growth inhibition assay		Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50=0.03004μM.	SANGER
SW780	Growth inhibition assay		Inhibition of human SW780 cell growth in a cell viability assay, IC50=0.03032μM.	SANGER
HTC-C3	Growth inhibition assay		Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50=0.03039μM.	SANGER
NCI-H1650	Growth inhibition assay		Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50=0.03043μM.	SANGER
NB5	Growth inhibition assay		Inhibition of human NB5 cell growth in a cell viability assay, IC50=0.03066μM.	SANGER
NCI-H2228	Growth inhibition assay		Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50=0.03091μM.	SANGER
SiHa	Growth inhibition assay		Inhibition of human SiHa cell growth in a cell viability assay, IC50=0.03106μM.	SANGER
MCF7	Growth inhibition assay		Inhibition of human MCF7 cell growth in a cell viability assay, IC50=0.03136μM.	SANGER
QIMR-WIL	Growth inhibition assay		Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50=0.03293μM.	SANGER
TGBC1TKB	Growth inhibition assay		Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50=0.03331μM.	SANGER
CAL-27	Growth inhibition assay		Inhibition of human CAL-27 cell growth in a cell viability assay, IC50=0.0334μM.	SANGER
OC-314	Growth inhibition assay		Inhibition of human OC-314 cell growth in a cell viability assay, IC50=0.03348μM.	SANGER
WM-115	Growth inhibition assay		Inhibition of human WM-115 cell growth in a cell viability assay, IC50=0.03401μM.	SANGER
RPMI-2650	Growth inhibition assay		Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50=0.03413μM.	SANGER
T98G	Growth inhibition assay		Inhibition of human T98G cell growth in a cell viability assay, IC50=0.03431μM.	SANGER
MDA-MB-453	Growth inhibition assay		Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50=0.03469μM.	SANGER
ETK-1	Growth inhibition assay		Inhibition of human ETK-1 cell growth in a cell viability assay, IC50=0.03502μM.	SANGER
SBC-1	Growth inhibition assay		Inhibition of human SBC-1 cell growth in a cell viability assay, IC50=0.03508μM.	SANGER
HCC1937	Growth inhibition assay		Inhibition of human HCC1937 cell growth in a cell viability assay, IC50=0.03516μM.	SANGER
BT-20	Growth inhibition assay		Inhibition of human BT-20 cell growth in a cell viability assay, IC50=0.03521μM.	SANGER
BB30-HNC	Growth inhibition assay		Inhibition of human BB30-HNC cell growth in a cell viability assay, IC50=0.03535μM.	SANGER
5637	Growth inhibition assay		Inhibition of human 5637 cell growth in a cell viability assay, IC50=0.03546μM.	SANGER
NCI-H650	Growth inhibition assay		Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50=0.03656μM.	SANGER
RPMI-7951	Growth inhibition assay		Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50=0.03657μM.	SANGER
KYSE-270	Growth inhibition assay		Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50=0.03709μM.	SANGER
KARPAS-299	Growth inhibition assay		Inhibition of human KARPAS-299 cell growth in a cell viability assay, IC50=0.03737μM.	SANGER
NY	Growth inhibition assay		Inhibition of human NY cell growth in a cell viability assay, IC50=0.0376μM.	SANGER
AsPC-1	Growth inhibition assay		Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50=0.0377μM.	SANGER
HPAF-II	Growth inhibition assay		Inhibition of human HPAF-II cell growth in a cell viability assay, IC50=0.03827μM.	SANGER
KYSE-450	Growth inhibition assay		Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50=0.03897μM.	SANGER
EKVX	Growth inhibition assay		Inhibition of human EKVX cell growth in a cell viability assay, IC50=0.03951μM.	SANGER
KG-1	Growth inhibition assay		Inhibition of human KG-1 cell growth in a cell viability assay, IC50=0.03969μM.	SANGER
EW-3	Growth inhibition assay		Inhibition of human EW-3 cell growth in a cell viability assay, IC50=0.03988μM.	SANGER
PANC-03-27	Growth inhibition assay		Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50=0.03991μM.	SANGER
ES6	Growth inhibition assay		Inhibition of human ES6 cell growth in a cell viability assay, IC50=0.03997μM.	SANGER
HCT-116	Growth inhibition assay		Inhibition of human HCT-116 cell growth in a cell viability assay, IC50=0.04003μM.	SANGER
SW620	Growth inhibition assay		Inhibition of human SW620 cell growth in a cell viability assay, IC50=0.04073μM.	SANGER
D-283MED	Growth inhibition assay		Inhibition of human D-283MED cell growth in a cell viability assay, IC50=0.04085μM.	SANGER
TK10	Growth inhibition assay		Inhibition of human TK10 cell growth in a cell viability assay, IC50=0.04233μM.	SANGER
COLO-678	Growth inhibition assay		Inhibition of human COLO-678 cell growth in a cell viability assay, IC50=0.04253μM.	SANGER
COLO-829	Growth inhibition assay		Inhibition of human COLO-829 cell growth in a cell viability assay, IC50=0.04311μM.	SANGER
NCI-H2342	Growth inhibition assay		Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50=0.04327μM.	SANGER
EC-GI-10	Growth inhibition assay		Inhibition of human EC-GI-10 cell growth in a cell viability assay, IC50=0.04463μM.	SANGER
NCI-H596	Growth inhibition assay		Inhibition of human NCI-H596 cell growth in a cell viability assay, IC50=0.04484μM.	SANGER
MFM-223	Growth inhibition assay		Inhibition of human MFM-223 cell growth in a cell viability assay, IC50=0.0452μM.	SANGER
TE-1	Growth inhibition assay		Inhibition of human TE-1 cell growth in a cell viability assay, IC50=0.04597μM.	SANGER
RPMI-8226	Growth inhibition assay		Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50=0.04599μM.	SANGER
TE-11	Growth inhibition assay		Inhibition of human TE-11 cell growth in a cell viability assay, IC50=0.04613μM.	SANGER
NCI-H1155	Growth inhibition assay		Inhibition of human NCI-H1155 cell growth in a cell viability assay, IC50=0.04621μM.	SANGER
A498	Growth inhibition assay		Inhibition of human A498 cell growth in a cell viability assay, IC50=0.04655μM.	SANGER
OS-RC-2	Growth inhibition assay		Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50=0.04771μM.	SANGER
ZR-75-30	Growth inhibition assay		Inhibition of human ZR-75-30 cell growth in a cell viability assay, IC50=0.04788μM.	SANGER
NB12	Growth inhibition assay		Inhibition of human NB12 cell growth in a cell viability assay, IC50=0.04796μM.	SANGER
LS-123	Growth inhibition assay		Inhibition of human LS-123 cell growth in a cell viability assay, IC50=0.04849μM.	SANGER
SKG-IIIa	Growth inhibition assay		Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50=0.04982μM.	SANGER
NCI-H2405	Growth inhibition assay		Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50=0.05105μM.	SANGER
IST-SL1	Growth inhibition assay		Inhibition of human IST-SL1 cell growth in a cell viability assay, IC50=0.05232μM.	SANGER
LAMA-84	Growth inhibition assay		Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50=0.05267μM.	SANGER
HCC70	Growth inhibition assay		Inhibition of human HCC70 cell growth in a cell viability assay, IC50=0.05309μM.	SANGER
SW626	Growth inhibition assay		Inhibition of human SW626 cell growth in a cell viability assay, IC50=0.05398μM.	SANGER
KYSE-70	Growth inhibition assay		Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50=0.05405μM.	SANGER
IST-MES1	Growth inhibition assay		Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50=0.05415μM.	SANGER
DJM-1	Growth inhibition assay		Inhibition of human DJM-1 cell growth in a cell viability assay, IC50=0.0543μM.	SANGER
LAN-6	Growth inhibition assay		Inhibition of human LAN-6 cell growth in a cell viability assay, IC50=0.05459μM.	SANGER
CP66-MEL	Growth inhibition assay		Inhibition of human CP66-MEL cell growth in a cell viability assay, IC50=0.05515μM.	SANGER
CAL-62	Growth inhibition assay		Inhibition of human CAL-62 cell growth in a cell viability assay, IC50=0.05519μM.	SANGER
HuP-T3	Growth inhibition assay		Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50=0.05575μM.	SANGER
LB2241-RCC	Growth inhibition assay		Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50=0.05636μM.	SANGER
NCI-H747	Growth inhibition assay		Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50=0.0574μM.	SANGER
H9	Growth inhibition assay		Inhibition of human H9 cell growth in a cell viability assay, IC50=0.05813μM.	SANGER
RH-1	Growth inhibition assay		Inhibition of human RH-1 cell growth in a cell viability assay, IC50=0.05817μM.	SANGER
AU565	Growth inhibition assay		Inhibition of human AU565 cell growth in a cell viability assay, IC50=0.05907μM.	SANGER
HCE-4	Growth inhibition assay		Inhibition of human HCE-4 cell growth in a cell viability assay, IC50=0.0591μM.	SANGER
MKN7	Growth inhibition assay		Inhibition of human MKN7 cell growth in a cell viability assay, IC50=0.061μM.	SANGER
EoL-1-cell	Growth inhibition assay		Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50=0.06203μM.	SANGER
SW900	Growth inhibition assay		Inhibition of human SW900 cell growth in a cell viability assay, IC50=0.06212μM.	SANGER
CAL-12T	Growth inhibition assay		Inhibition of human CAL-12T cell growth in a cell viability assay, IC50=0.063μM.	SANGER
NCI-H2052	Growth inhibition assay		Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50=0.06331μM.	SANGER
BFTC-909	Growth inhibition assay		Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50=0.0635μM.	SANGER
KP-N-YN	Growth inhibition assay		Inhibition of human KP-N-YN cell growth in a cell viability assay, IC50=0.06561μM.	SANGER
HL-60	Growth inhibition assay		Inhibition of human HL-60 cell growth in a cell viability assay, IC50=0.06677μM.	SANGER
LB2518-MEL	Growth inhibition assay		Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50=0.06694μM.	SANGER
Detroit562	Growth inhibition assay		Inhibition of human Detroit562 cell growth in a cell viability assay, IC50=0.0689μM.	SANGER
MHH-NB-11	Growth inhibition assay		Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50=0.06913μM.	SANGER
YAPC	Growth inhibition assay		Inhibition of human YAPC cell growth in a cell viability assay, IC50=0.07034μM.	SANGER
COLO-824	Growth inhibition assay		Inhibition of human COLO-824 cell growth in a cell viability assay, IC50=0.07181μM.	SANGER
CAL-85-1	Growth inhibition assay		Inhibition of human CAL-85-1 cell growth in a cell viability assay, IC50=0.07266μM.	SANGER
SK-MEL-2	Growth inhibition assay		Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50=0.07316μM.	SANGER
RH-18	Growth inhibition assay		Inhibition of human RH-18 cell growth in a cell viability assay, IC50=0.07417μM.	SANGER
EW-22	Growth inhibition assay		Inhibition of human EW-22 cell growth in a cell viability assay, IC50=0.07468μM.	SANGER
SK-NEP-1	Growth inhibition assay		Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50=0.07614μM.	SANGER
RVH-421	Growth inhibition assay		Inhibition of human RVH-421 cell growth in a cell viability assay, IC50=0.07618μM.	SANGER
OMC-1	Growth inhibition assay		Inhibition of human OMC-1 cell growth in a cell viability assay, IC50=0.07714μM.	SANGER
LoVo	Growth inhibition assay		Inhibition of human LoVo cell growth in a cell viability assay, IC50=0.07856μM.	SANGER
D-392MG	Growth inhibition assay		Inhibition of human D-392MG cell growth in a cell viability assay, IC50=0.07865μM.	SANGER
HCC1187	Growth inhibition assay		Inhibition of human HCC1187 cell growth in a cell viability assay, IC50=0.07933μM.	SANGER
SK-MEL-28	Growth inhibition assay		Inhibition of human SK-MEL-28 cell growth in a cell viability assay, IC50=0.07974μM.	SANGER
KP-N-YS	Growth inhibition assay		Inhibition of human KP-N-YS cell growth in a cell viability assay, IC50=0.07987μM.	SANGER
SK-N-FI	Growth inhibition assay		Inhibition of human SK-N-FI cell growth in a cell viability assay, IC50=0.08148μM.	SANGER
OAW-42	Growth inhibition assay		Inhibition of human OAW-42 cell growth in a cell viability assay, IC50=0.08159μM.	SANGER
LS-513	Growth inhibition assay		Inhibition of human LS-513 cell growth in a cell viability assay, IC50=0.08202μM.	SANGER
SW1088	Growth inhibition assay		Inhibition of human SW1088 cell growth in a cell viability assay, IC50=0.08214μM.	SANGER
EFM-19	Growth inhibition assay		Inhibition of human EFM-19 cell growth in a cell viability assay, IC50=0.08252μM.	SANGER
NCI-H1651	Growth inhibition assay		Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50=0.08292μM.	SANGER
BPH-1	Growth inhibition assay		Inhibition of human BPH-1 cell growth in a cell viability assay, IC50=0.08314μM.	SANGER
MMAC-SF	Growth inhibition assay		Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50=0.08429μM.	SANGER
IA-LM	Growth inhibition assay		Inhibition of human IA-LM cell growth in a cell viability assay, IC50=0.08443μM.	SANGER
A3-KAW	Growth inhibition assay		Inhibition of human A3-KAW cell growth in a cell viability assay, IC50=0.08648μM.	SANGER
NCI-H1437	Growth inhibition assay		Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50=0.08766μM.	SANGER
LN-405	Growth inhibition assay		Inhibition of human LN-405 cell growth in a cell viability assay, IC50=0.08779μM.	SANGER
NCI-H446	Growth inhibition assay		Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50=0.09008μM.	SANGER
NCI-H1092	Growth inhibition assay		Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50=0.09011μM.	SANGER
KYSE-150	Growth inhibition assay		Inhibition of human KYSE-150 cell growth in a cell viability assay, IC50=0.09498μM.	SANGER
KALS-1	Growth inhibition assay		Inhibition of human KALS-1 cell growth in a cell viability assay, IC50=0.09625μM.	SANGER
SJRH30	Growth inhibition assay		Inhibition of human SJRH30 cell growth in a cell viability assay, IC50=0.09996μM.	SANGER
LS-411N	Growth inhibition assay		Inhibition of human LS-411N cell growth in a cell viability assay, IC50=0.10177μM.	SANGER
ESS-1	Growth inhibition assay		Inhibition of human ESS-1 cell growth in a cell viability assay, IC50=0.10214μM.	SANGER
C2BBe1	Growth inhibition assay		Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50=0.10267μM.	SANGER
KYSE-520	Growth inhibition assay		Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50=0.10382μM.	SANGER
IGROV-1	Growth inhibition assay		Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50=0.10398μM.	SANGER
MOLT-4	Growth inhibition assay		Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50=0.10468μM.	SANGER
MEG-01	Growth inhibition assay		Inhibition of human MEG-01 cell growth in a cell viability assay, IC50=0.10505μM.	SANGER
SNB75	Growth inhibition assay		Inhibition of human SNB75 cell growth in a cell viability assay, IC50=0.10509μM.	SANGER
SW837	Growth inhibition assay		Inhibition of human SW837 cell growth in a cell viability assay, IC50=0.10658μM.	SANGER
GMS-10	Growth inhibition assay		Inhibition of human GMS-10 cell growth in a cell viability assay, IC50=0.10669μM.	SANGER
BHY	Growth inhibition assay		Inhibition of human BHY cell growth in a cell viability assay, IC50=0.10706μM.	SANGER
HSC-2	Growth inhibition assay		Inhibition of human HSC-2 cell growth in a cell viability assay, IC50=0.1074μM.	SANGER
A4-Fuk	Growth inhibition assay		Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50=0.10761μM.	SANGER
VMRC-RCZ	Growth inhibition assay		Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50=0.10762μM.	SANGER
SW48	Growth inhibition assay		Inhibition of human SW48 cell growth in a cell viability assay, IC50=0.10778μM.	SANGER
PANC-10-05	Growth inhibition assay		Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50=0.10979μM.	SANGER
KYSE-510	Growth inhibition assay		Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50=0.11035μM.	SANGER
HCC2998	Growth inhibition assay		Inhibition of human HCC2998 cell growth in a cell viability assay, IC50=0.11066μM.	SANGER
SW962	Growth inhibition assay		Inhibition of human SW962 cell growth in a cell viability assay, IC50=0.11128μM.	SANGER
DU-4475	Growth inhibition assay		Inhibition of human DU-4475 cell growth in a cell viability assay, IC50=0.1117μM.	SANGER
CAS-1	Growth inhibition assay		Inhibition of human CAS-1 cell growth in a cell viability assay, IC50=0.11615μM.	SANGER
BEN	Growth inhibition assay		Inhibition of human BEN cell growth in a cell viability assay, IC50=0.11639μM.	SANGER
TE-9	Growth inhibition assay		Inhibition of human TE-9 cell growth in a cell viability assay, IC50=0.11735μM.	SANGER
SCC-9	Growth inhibition assay		Inhibition of human SCC-9 cell growth in a cell viability assay, IC50=0.1207μM.	SANGER
LU-139	Growth inhibition assay		Inhibition of human LU-139 cell growth in a cell viability assay, IC50=0.12082μM.	SANGER
M14	Growth inhibition assay		Inhibition of human M14 cell growth in a cell viability assay, IC50=0.12231μM.	SANGER
HOP-62	Growth inhibition assay		Inhibition of human HOP-62 cell growth in a cell viability assay, IC50=0.12241μM.	SANGER
NCI-H720	Growth inhibition assay		Inhibition of human NCI-H720 cell growth in a cell viability assay, IC50=0.12372μM.	SANGER
NCI-H810	Growth inhibition assay		Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50=0.12501μM.	SANGER
BB49-HNC	Growth inhibition assay		Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50=0.12558μM.	SANGER
A431	Growth inhibition assay		Inhibition of human A431 cell growth in a cell viability assay, IC50=0.12588μM.	SANGER
HAL-01	Growth inhibition assay		Inhibition of human HAL-01 cell growth in a cell viability assay, IC50=0.12809μM.	SANGER
NCI-H2122	Growth inhibition assay		Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50=0.13028μM.	SANGER
NCI-H226	Growth inhibition assay		Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50=0.13147μM.	SANGER
NH-12	Growth inhibition assay		Inhibition of human NH-12 cell growth in a cell viability assay, IC50=0.13425μM.	SANGER
NCI-H520	Growth inhibition assay		Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50=0.13483μM.	SANGER
OCI-AML2	Growth inhibition assay		Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50=0.13558μM.	SANGER
MDA-MB-415	Growth inhibition assay		Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50=0.13655μM.	SANGER
TE-6	Growth inhibition assay		Inhibition of human TE-6 cell growth in a cell viability assay, IC50=0.139μM.	SANGER
SW1783	Growth inhibition assay		Inhibition of human SW1783 cell growth in a cell viability assay, IC50=0.13904μM.	SANGER
DB	Growth inhibition assay		Inhibition of human DB cell growth in a cell viability assay, IC50=0.1414μM.	SANGER
NB6	Growth inhibition assay		Inhibition of human NB6 cell growth in a cell viability assay, IC50=0.14232μM.	SANGER
MZ1-PC	Growth inhibition assay		Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50=0.14379μM.	SANGER
KMOE-2	Growth inhibition assay		Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50=0.14527μM.	SANGER
EFO-21	Growth inhibition assay		Inhibition of human EFO-21 cell growth in a cell viability assay, IC50=0.14938μM.	SANGER
HCT-15	Growth inhibition assay		Inhibition of human HCT-15 cell growth in a cell viability assay, IC50=0.15005μM.	SANGER
MS-1	Growth inhibition assay		Inhibition of human MS-1 cell growth in a cell viability assay, IC50=0.1657μM.	SANGER
AM-38	Growth inhibition assay		Inhibition of human AM-38 cell growth in a cell viability assay, IC50=0.16878μM.	SANGER
LOXIMVI	Growth inhibition assay		Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50=0.17147μM.	SANGER
COLO-741	Growth inhibition assay		Inhibition of human COLO-741 cell growth in a cell viability assay, IC50=0.17614μM.	SANGER
KINGS-1	Growth inhibition assay		Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50=0.17712μM.	SANGER
NCI-H1623	Growth inhibition assay		Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50=0.17935μM.	SANGER
NCI-H1838	Growth inhibition assay		Inhibition of human NCI-H1838 cell growth in a cell viability assay, IC50=0.18381μM.	SANGER
COLO-680N	Growth inhibition assay		Inhibition of human COLO-680N cell growth in a cell viability assay, IC50=0.18702μM.	SANGER
NCI-H1573	Growth inhibition assay		Inhibition of human NCI-H1573 cell growth in a cell viability assay, IC50=0.1888μM.	SANGER
SK-N-DZ	Growth inhibition assay		Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50=0.18927μM.	SANGER
8305C	Growth inhibition assay		Inhibition of human 8305C cell growth in a cell viability assay, IC50=0.1925μM.	SANGER
OCUB-M	Growth inhibition assay		Inhibition of human OCUB-M cell growth in a cell viability assay, IC50=0.19545μM.	SANGER
LB771-HNC	Growth inhibition assay		Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50=0.20018μM.	SANGER
NCI-H1793	Growth inhibition assay		Inhibition of human NCI-H1793 cell growth in a cell viability assay, IC50=0.2097μM.	SANGER
HT-3	Growth inhibition assay		Inhibition of human HT-3 cell growth in a cell viability assay, IC50=0.21164μM.	SANGER
LCLC-97TM1	Growth inhibition assay		Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50=0.21748μM.	SANGER
TE-12	Growth inhibition assay		Inhibition of human TE-12 cell growth in a cell viability assay, IC50=0.22078μM.	SANGER
HCC2218	Growth inhibition assay		Inhibition of human HCC2218 cell growth in a cell viability assay, IC50=0.22093μM.	SANGER
GP5d	Growth inhibition assay		Inhibition of human GP5d cell growth in a cell viability assay, IC50=0.2262μM.	SANGER
SNU-C2B	Growth inhibition assay		Inhibition of human SNU-C2B cell growth in a cell viability assay, IC50=0.22661μM.	SANGER
U-87-MG	Growth inhibition assay		Inhibition of human U-87-MG cell growth in a cell viability assay, IC50=0.22753μM.	SANGER
HH	Growth inhibition assay		Inhibition of human HH cell growth in a cell viability assay, IC50=0.22843μM.	SANGER
SH-4	Growth inhibition assay		Inhibition of human SH-4 cell growth in a cell viability assay, IC50=0.23264μM.	SANGER
LCLC-103H	Growth inhibition assay		Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50=0.23712μM.	SANGER
KNS-42	Growth inhibition assay		Inhibition of human KNS-42 cell growth in a cell viability assay, IC50=0.24283μM.	SANGER
CW-2	Growth inhibition assay		Inhibition of human CW-2 cell growth in a cell viability assay, IC50=0.25767μM.	SANGER
NCI-N87	Growth inhibition assay		Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50=0.2642μM.	SANGER
OAW-28	Growth inhibition assay		Inhibition of human OAW-28 cell growth in a cell viability assay, IC50=0.28348μM.	SANGER
NCI-H1648	Growth inhibition assay		Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50=0.28554μM.	SANGER
D-263MG	Growth inhibition assay		Inhibition of human D-263MG cell growth in a cell viability assay, IC50=0.28767μM.	SANGER
RS4-11	Growth inhibition assay		Inhibition of human RS4-11 cell growth in a cell viability assay, IC50=0.28947μM.	SANGER
GI-ME-N	Growth inhibition assay		Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50=0.29033μM.	SANGER
JVM-3	Growth inhibition assay		Inhibition of human JVM-3 cell growth in a cell viability assay, IC50=0.29281μM.	SANGER
MEL-HO	Growth inhibition assay		Inhibition of human MEL-HO cell growth in a cell viability assay, IC50=0.30023μM.	SANGER
MSTO-211H	Growth inhibition assay		Inhibition of human MSTO-211H cell growth in a cell viability assay, IC50=0.30254μM.	SANGER
NCI-H1792	Growth inhibition assay		Inhibition of human NCI-H1792 cell growth in a cell viability assay, IC50=0.30568μM.	SANGER
TE-10	Growth inhibition assay		Inhibition of human TE-10 cell growth in a cell viability assay, IC50=0.31694μM.	SANGER
NCI-H2009	Growth inhibition assay		Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50=0.31749μM.	SANGER
DOHH-2	Growth inhibition assay		Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50=0.32805μM.	SANGER
GCIY	Growth inhibition assay		Inhibition of human GCIY cell growth in a cell viability assay, IC50=0.32874μM.	SANGER
SCH	Growth inhibition assay		Inhibition of human SCH cell growth in a cell viability assay, IC50=0.3391μM.	SANGER
KLE	Growth inhibition assay		Inhibition of human KLE cell growth in a cell viability assay, IC50=0.38036μM.	SANGER
BE-13	Growth inhibition assay		Inhibition of human BE-13 cell growth in a cell viability assay, IC50=0.39158μM.	SANGER
CAMA-1	Growth inhibition assay		Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50=0.39459μM.	SANGER
HC-1	Growth inhibition assay		Inhibition of human HC-1 cell growth in a cell viability assay, IC50=0.39991μM.	SANGER
LU-134-A	Growth inhibition assay		Inhibition of human LU-134-A cell growth in a cell viability assay, IC50=0.40045μM.	SANGER
HCC38	Growth inhibition assay		Inhibition of human HCC38 cell growth in a cell viability assay, IC50=0.41829μM.	SANGER
SW872	Growth inhibition assay		Inhibition of human SW872 cell growth in a cell viability assay, IC50=0.44657μM.	SANGER
BxPC-3	Growth inhibition assay		Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50=0.47501μM.	SANGER
UACC-893	Growth inhibition assay		Inhibition of human UACC-893 cell growth in a cell viability assay, IC50=0.48439μM.	SANGER
KURAMOCHI	Growth inhibition assay		Inhibition of human KURAMOCHI cell growth in a cell viability assay, IC50=0.48728μM.	SANGER
DU-145	Growth inhibition assay		Inhibition of human DU-145 cell growth in a cell viability assay, IC50=0.50043μM.	SANGER
SK-MES-1	Growth inhibition assay		Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50=0.50677μM.	SANGER
NKM-1	Growth inhibition assay		Inhibition of human NKM-1 cell growth in a cell viability assay, IC50=0.50925μM.	SANGER
TGBC11TKB	Growth inhibition assay		Inhibition of human TGBC11TKB cell growth in a cell viability assay, IC50=0.51476μM.	SANGER
HT-1376	Growth inhibition assay		Inhibition of human HT-1376 cell growth in a cell viability assay, IC50=0.53816μM.	SANGER
LU-135	Growth inhibition assay		Inhibition of human LU-135 cell growth in a cell viability assay, IC50=0.54563μM.	SANGER
SCC-4	Growth inhibition assay		Inhibition of human SCC-4 cell growth in a cell viability assay, IC50=0.54737μM.	SANGER
BALL-1	Growth inhibition assay		Inhibition of human BALL-1 cell growth in a cell viability assay, IC50=0.55558μM.	SANGER
NCI-H1304	Growth inhibition assay		Inhibition of human NCI-H1304 cell growth in a cell viability assay, IC50=0.55573μM.	SANGER
CaR-1	Growth inhibition assay		Inhibition of human CaR-1 cell growth in a cell viability assay, IC50=0.58618μM.	SANGER
GR-ST	Growth inhibition assay		Inhibition of human GR-ST cell growth in a cell viability assay, IC50=0.6283μM.	SANGER
COR-L88	Growth inhibition assay		Inhibition of human COR-L88 cell growth in a cell viability assay, IC50=0.64357μM.	SANGER
NCI-H526	Growth inhibition assay		Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50=0.67186μM.	SANGER
MZ2-MEL	Growth inhibition assay		Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50=0.71038μM.	SANGER
MDA-MB-175-VII	Growth inhibition assay		Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50=0.72931μM.	SANGER
KGN	Growth inhibition assay		Inhibition of human KGN cell growth in a cell viability assay, IC50=0.75883μM.	SANGER
KARPAS-45	Growth inhibition assay		Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50=0.76422μM.	SANGER
SK-LMS-1	Growth inhibition assay		Inhibition of human SK-LMS-1 cell growth in a cell viability assay, IC50=0.77309μM.	SANGER
MFE-280	Growth inhibition assay		Inhibition of human MFE-280 cell growth in a cell viability assay, IC50=0.80193μM.	SANGER
ALL-PO	Growth inhibition assay		Inhibition of human ALL-PO cell growth in a cell viability assay, IC50=0.8079μM.	SANGER
DoTc2-4510	Growth inhibition assay		Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50=0.83126μM.	SANGER
SW1417	Growth inhibition assay		Inhibition of human SW1417 cell growth in a cell viability assay, IC50=0.84154μM.	SANGER
KE-37	Growth inhibition assay		Inhibition of human KE-37 cell growth in a cell viability assay, IC50=0.87226μM.	SANGER
GAK	Growth inhibition assay		Inhibition of human GAK cell growth in a cell viability assay, IC50=0.91357μM.	SANGER
SK-MEL-1	Growth inhibition assay		Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50=0.94883μM.	SANGER
HT	Growth inhibition assay		Inhibition of human HT cell growth in a cell viability assay, IC50=0.96058μM.	SANGER
LU-99A	Growth inhibition assay		Inhibition of human LU-99A cell growth in a cell viability assay, IC50=0.98114μM.	SANGER
EW-18	Growth inhibition assay		Inhibition of human EW-18 cell growth in a cell viability assay, IC50=0.99505μM.	SANGER
P30-OHK	Growth inhibition assay		Inhibition of human P30-OHK cell growth in a cell viability assay, IC50=1.06027μM.	SANGER
CAPAN-1	Growth inhibition assay		Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50=1.06876μM.	SANGER
SK-MEL-24	Growth inhibition assay		Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50=1.0762μM.	SANGER
ML-2	Growth inhibition assay		Inhibition of human ML-2 cell growth in a cell viability assay, IC50=1.14212μM.	SANGER
SK-HEP-1	Growth inhibition assay		Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50=1.15753μM.	SANGER
HT55	Growth inhibition assay		Inhibition of human HT55 cell growth in a cell viability assay, IC50=1.17705μM.	SANGER
Calu-6	Growth inhibition assay		Inhibition of human Calu-6 cell growth in a cell viability assay, IC50=1.19035μM.	SANGER
Ca-Ski	Growth inhibition assay		Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50=1.24599μM.	SANGER
CAL-54	Growth inhibition assay		Inhibition of human CAL-54 cell growth in a cell viability assay, IC50=1.28131μM.	SANGER
HMV-II	Growth inhibition assay		Inhibition of human HMV-II cell growth in a cell viability assay, IC50=1.30192μM.	SANGER
DMS-79	Growth inhibition assay		Inhibition of human DMS-79 cell growth in a cell viability assay, IC50=1.35288μM.	SANGER
NCI-H2291	Growth inhibition assay		Inhibition of human NCI-H2291 cell growth in a cell viability assay, IC50=1.35312μM.	SANGER
SK-MEL-3	Growth inhibition assay		Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50=1.42951μM.	SANGER
COR-L23	Growth inhibition assay		Inhibition of human COR-L23 cell growth in a cell viability assay, IC50=1.4298μM.	SANGER
SHP-77	Growth inhibition assay		Inhibition of human SHP-77 cell growth in a cell viability assay, IC50=1.45832μM.	SANGER
KM12	Growth inhibition assay		Inhibition of human KM12 cell growth in a cell viability assay, IC50=1.47664μM.	SANGER
K-562	Growth inhibition assay		Inhibition of human K-562 cell growth in a cell viability assay, IC50=1.47985μM.	SANGER
SW1463	Growth inhibition assay		Inhibition of human SW1463 cell growth in a cell viability assay, IC50=1.56644μM.	SANGER
MC116	Growth inhibition assay		Inhibition of human MC116 cell growth in a cell viability assay, IC50=1.59879μM.	SANGER
no-10	Growth inhibition assay		Inhibition of human no-10 cell growth in a cell viability assay, IC50=1.60982μM.	SANGER
T84	Growth inhibition assay		Inhibition of human T84 cell growth in a cell viability assay, IC50=1.7516μM.	SANGER
IGR-1	Growth inhibition assay		Inhibition of human IGR-1 cell growth in a cell viability assay, IC50=1.75671μM.	SANGER
U-118-MG	Growth inhibition assay		Inhibition of human U-118-MG cell growth in a cell viability assay, IC50=1.88558μM.	SANGER
NCI-H2087	Growth inhibition assay		Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50=1.89044μM.	SANGER
D-542MG	Growth inhibition assay		Inhibition of human D-542MG cell growth in a cell viability assay, IC50=1.90441μM.	SANGER
NCI-H727	Growth inhibition assay		Inhibition of human NCI-H727 cell growth in a cell viability assay, IC50=1.94908μM.	SANGER
SW684	Growth inhibition assay		Inhibition of human SW684 cell growth in a cell viability assay, IC50=2.03866μM.	SANGER
Capan-2	Growth inhibition assay		Inhibition of human Capan-2 cell growth in a cell viability assay, IC50=2.04183μM.	SANGER
HT-29	Growth inhibition assay		Inhibition of human HT-29 cell growth in a cell viability assay, IC50=2.04276μM.	SANGER
KASUMI-1	Growth inhibition assay		Inhibition of human KASUMI-1 cell growth in a cell viability assay, IC50=2.09155μM.	SANGER
ATN-1	Growth inhibition assay		Inhibition of human ATN-1 cell growth in a cell viability assay, IC50=2.0956μM.	SANGER
JVM-2	Growth inhibition assay		Inhibition of human JVM-2 cell growth in a cell viability assay, IC50=2.14047μM.	SANGER
SK-MEL-30	Growth inhibition assay		Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50=2.38457μM.	SANGER
COLO-668	Growth inhibition assay		Inhibition of human COLO-668 cell growth in a cell viability assay, IC50=2.50458μM.	SANGER
EM-2	Growth inhibition assay		Inhibition of human EM-2 cell growth in a cell viability assay, IC50=2.51815μM.	SANGER
UMC-11	Growth inhibition assay		Inhibition of human UMC-11 cell growth in a cell viability assay, IC50=2.60698μM.	SANGER
MG-63	Growth inhibition assay		Inhibition of human MG-63 cell growth in a cell viability assay, IC50=2.8112μM.	SANGER
NCI-SNU-5	Growth inhibition assay		Inhibition of human NCI-SNU-5 cell growth in a cell viability assay, IC50=2.863μM.	SANGER
NOMO-1	Growth inhibition assay		Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50=2.90568μM.	SANGER
NCI-H209	Growth inhibition assay		Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50=3.00673μM.	SANGER
CTV-1	Growth inhibition assay		Inhibition of human CTV-1 cell growth in a cell viability assay, IC50=3.01648μM.	SANGER
NCI-H1770	Growth inhibition assay		Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50=3.02207μM.	SANGER
RCM-1	Growth inhibition assay		Inhibition of human RCM-1 cell growth in a cell viability assay, IC50=3.03156μM.	SANGER
Calu-3	Growth inhibition assay		Inhibition of human Calu-3 cell growth in a cell viability assay, IC50=3.16226μM.	SANGER
NCI-H630	Growth inhibition assay		Inhibition of human NCI-H630 cell growth in a cell viability assay, IC50=3.43203μM.	SANGER
SW1116	Growth inhibition assay		Inhibition of human SW1116 cell growth in a cell viability assay, IC50=3.62799μM.	SANGER
RMG-I	Growth inhibition assay		Inhibition of human RMG-I cell growth in a cell viability assay, IC50=3.84056μM.	SANGER
RCC10RGB	Growth inhibition assay		Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50=4.53554μM.	SANGER
C3A	Growth inhibition assay		Inhibition of human C3A cell growth in a cell viability assay, IC50=4.63097μM.	SANGER
C8166	Growth inhibition assay		Inhibition of human C8166 cell growth in a cell viability assay, IC50=4.94603μM.	SANGER
MOLT-13	Growth inhibition assay		Inhibition of human MOLT-13 cell growth in a cell viability assay, IC50=5.5543μM.	SANGER
NCI-H2029	Growth inhibition assay		Inhibition of human NCI-H2029 cell growth in a cell viability assay, IC50=5.59003μM.	SANGER
HDLM-2	Growth inhibition assay		Inhibition of human HDLM-2 cell growth in a cell viability assay, IC50=5.67384μM.	SANGER
ACHN	Growth inhibition assay		Inhibition of human ACHN cell growth in a cell viability assay, IC50=5.71551μM.	SANGER
NCI-H69	Growth inhibition assay		Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50=5.96973μM.	SANGER
ECC10	Growth inhibition assay		Inhibition of human ECC10 cell growth in a cell viability assay, IC50=6.27244μM.	SANGER
CFPAC-1	Growth inhibition assay		Inhibition of human CFPAC-1 cell growth in a cell viability assay, IC50=6.38606μM.	SANGER
KU812	Growth inhibition assay		Inhibition of human KU812 cell growth in a cell viability assay, IC50=7.31846μM.	SANGER
L-428	Growth inhibition assay		Inhibition of human L-428 cell growth in a cell viability assay, IC50=7.64645μM.	SANGER
LU-65	Growth inhibition assay		Inhibition of human LU-65 cell growth in a cell viability assay, IC50=7.66066μM.	SANGER
KY821	Growth inhibition assay		Inhibition of human KY821 cell growth in a cell viability assay, IC50=9.74408μM.	SANGER
HCC1569	Growth inhibition assay		Inhibition of human HCC1569 cell growth in a cell viability assay, IC50=10.3717μM.	SANGER
OE33	Growth inhibition assay		Inhibition of human OE33 cell growth in a cell viability assay, IC50=11.9163μM.	SANGER
NCI-H460	Growth inhibition assay		Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50=11.9629μM.	SANGER
CCRF-CEM	Growth inhibition assay		Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50=12.0256μM.	SANGER
MFH-ino	Growth inhibition assay		Inhibition of human MFH-ino cell growth in a cell viability assay, IC50=12.2311μM.	SANGER
HCC1954	Growth inhibition assay		Inhibition of human HCC1954 cell growth in a cell viability assay, IC50=12.6636μM.	SANGER
SW948	Growth inhibition assay		Inhibition of human SW948 cell growth in a cell viability assay, IC50=14.1953μM.	SANGER
NCI-H82	Growth inhibition assay		Inhibition of human NCI-H82 cell growth in a cell viability assay, IC50=14.6264μM.	SANGER
KM-H2	Growth inhibition assay		Inhibition of human KM-H2 cell growth in a cell viability assay, IC50=15.7903μM.	SANGER
OE19	Growth inhibition assay		Inhibition of human OE19 cell growth in a cell viability assay, IC50=16.5176μM.	SANGER
COLO-320-HSR	Growth inhibition assay		Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50=16.92μM.	SANGER
NCI-H441	Growth inhibition assay		Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50=20.1493μM.	SANGER
A388	Growth inhibition assay		Inhibition of human A388 cell growth in a cell viability assay, IC50=21.4044μM.	SANGER
NCI-H1993	Growth inhibition assay		Inhibition of human NCI-H1993 cell growth in a cell viability assay, IC50=22.4278μM.	SANGER
LS-1034	Growth inhibition assay		Inhibition of human LS-1034 cell growth in a cell viability assay, IC50=23.2936μM.	SANGER
NCI-H1666	Growth inhibition assay		Inhibition of human NCI-H1666 cell growth in a cell viability assay, IC50=33.2038μM.	SANGER
NCI-H1975	Growth inhibition assay		Inhibition of human NCI-H1975 cell growth in a cell viability assay, IC50=35.902μM.	SANGER
Click to View More Cell Line Experimental Data

Biological Activity

Description

Targets

HSP70 ^[1]
(Cell-free assay)

In vitro
In vitro	Elesclomol significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells. Elesclomol (100 nM) rapidly induces Hsp70 RNA levels with a 4.8-fold increase at 1 hour and a 160-fold increase at 6 hours in Ramos Burkitt's lymphoma B cells in consistent with the intracellular ROS content which increases by 20% as early as 0.5 hour and 385% at 6 hours, and the induction of Hsp70 can be blocked by antioxidants NAC and Tiron pretreatment. Elesclomol increases the number of early and late apoptotic cells with 3.7- and 11-fold through the induction of oxidative stress, which can be completely blocked by NAC, while having little effect on normal cells. ^[1] Elesclomol significantly inhibits the cell viability of SK-MEL-5, MCF-7, and HL-60 with IC50 of 110 nM, 24 nM and 9 nM, respectively. ^[2] Elesclomol induces copper-dependent ROS generation and cytoxicity in yeast. Instead of working through a specific cellular protein target, Elesclomol interacts with the electron transport chain (ETC), a biologically coherent set of processes occurring in the mitochondrion, to generate high levels of ROS within the organelle and consequently cell death. ^[3]
Cell Research	Cell lines	Hs294T, HSB2, and Ramos
	Concentrations	Dissolved in DMSO at a concentration of 10 mM, final concentrations ~500 nM
	Incubation Time	18, or 24 hours
	Method	Cells are treated with various concentrations of Elesclomol for 18 or 24 hours. The level of intracellular ROS is monitored using the DCFDA probe, which emits a green fluorescence on oxidation. Cell death is determined by flow cytometry of cells double stained with Annexin V/FITC and propidium iodide (PI) using a Vybrant Apoptosis assay kit.

In Vivo
In vivo	Although Elesclomol (25-100 mg/kg) as a single agent shows no antitumor activity in nude mouse xenograft models of human breast cancers (MDA435, MCF7 and ZR-75-1), lung cancer (RER) or lymphoma (U937), Elesclomol substantially enhances the efficacy of chemotherapeutic agents in these models, both in terms of tumor regression and extended survival of mice. ^[4]
Animal Research	Animal Models	Female CD-1 nude mice bearing established MDA435 breast cancer xenograft tumors
	Dosages	~100 mg/kg
	Administration	Intravenous injection

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT00827203	Suspended	Metastatic Solid Tumors	Synta Pharmaceuticals Corp.	January 2009	Phase 1
NCT00808418	Completed	Prostate Cancer	Synta Pharmaceuticals Corp.	November 2008	Phase 1

References

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Chemical Information & Solubility

Molecular Weight	400.5	Formula	C₁₉H₂₀N₄O₂S₂
CAS No.	488832-69-5	SDF	Download Elesclomol (STA-4783) SDF
Smiles	CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 80 mg/mL ( (199.75 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molecular Weight Calculator

In vivo Batch: Add solvents to the product individually and in order.					In vivo Formulation Calculator
	Clear solution	5%DMSO 1 10%PEG300 2 85%saline	0.6mg/ml (1.50mM)	Taking the 1 mL working solution as an example, add 50 μL of 12 mg/ml clarified DMSO stock solution to 100 μL of PEG300, mix evenly to clarify it; then continue to add 850 μL of saline to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.	In vivo Formulation Calculator
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O	10.0mg/ml (24.97mM)	Taking the 1 mL working solution as an example, add 50 μL of 200 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O	10.0mg/ml (24.97mM)	Taking the 1 mL working solution as an example, add 50 μL of 200 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to make it clear; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

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Frequently Asked Questions

Question 1:
How can we use the compound for in vivo mouse studies?

Answer:
S1052 in 1% DMSO+30% polyethylene glycol+1% Tween 80 is a suspension, it is fine for oral administration. You can also dissolve S1052 in 0.5-1% CMC-Na solution and treat the mice by oral gavage.

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