Home GPCR & G Protein Adenosine Receptor agonist 5'-Deoxy-5'-(methylthio)adenosine For research use only.

5'-Deoxy-5'-(methylthio)adenosine

Synonyms: Methylthioadenosine, MTA

5'-Deoxy-5'-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of 0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively.

5'-Deoxy-5'-(methylthio)adenosine Chemical Structure

5'-Deoxy-5'-(methylthio)adenosine Chemical Structure

CAS No. 2457-80-9

Purity & Quality Control

Batch: E403201 DMSO]59 mg/mL]false]Water]6 mg/mL]false]Ethanol]3 mg/mL]false Purity: 99.03%
99.03

5'-Deoxy-5'-(methylthio)adenosine Related Products

Biological Activity

Description 5'-Deoxy-5'-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of 0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively.
Targets
A1 [1] A3 [1] A2A [1] A2B [1]
0.15 μM(Ki) 0.68 μM(Ki) 1.13 μM(Ki) 13.9 μM(Ki)
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06227390 Recruiting
Pulp Disease Dental
British University In Egypt
 October 15 2023 Not Applicable
NCT04243733 Unknown status
Irreversible Pulpitis
Suez Canal University
 October 10 2018 Not Applicable

Chemical Information & Solubility

Molecular Weight 297.34 Formula

C11H15N5O3S
CAS No. 2457-80-9 SDF Download 5'-Deoxy-5'-(methylthio)adenosine SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 59 mg/mL ( (198.42 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 6 mg/mL

Ethanol : 3 mg/mL


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