PP2A

PP2A Products

All (5)
PP2A Inhibitors (4)
PP2A Activator (1)
New PP2A Products

Catalog No.	Product Name	Information	Product Use Citations
S7537	LB-100	LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.	Cell Death Dis, 2024, 15(2):121 Eur J Immunol, 2024, e2350825. Blood Cancer J, 2023, 13(1):106
S8774	DT-061 (SMAP)	DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.	Cell Rep, 2024, 43(4):114054 Allergy Asthma Immunol Res, 2024, 16(1):71-90 Allergy Asthma Immunol Res, 2024, 16(4):422-433
S8248	IQ-1	IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.	Haematologica, 2022, 10.3324/haematol.2022.280760 Neoplasia, 2020, 23(1):1-11 Cell Mol Life Sci, 2019, 76(14):2817-2832
S0308	AMZ30	AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S3861	Sodium Demethylcantharidate	Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
S7537	LB-100	LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.	Cell Death Dis, 2024, 15(2):121 Eur J Immunol, 2024, e2350825. Blood Cancer J, 2023, 13(1):106
S8248	IQ-1	IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.	Haematologica, 2022, 10.3324/haematol.2022.280760 Neoplasia, 2020, 23(1):1-11 Cell Mol Life Sci, 2019, 76(14):2817-2832
S0308	AMZ30	AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S3861	Sodium Demethylcantharidate	Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
S8774	DT-061 (SMAP)	DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.	Cell Rep, 2024, 43(4):114054 Allergy Asthma Immunol Res, 2024, 16(1):71-90 Allergy Asthma Immunol Res, 2024, 16(4):422-433

Choose Selective PP2A Inhibitors