Home Peptide Products Bulevirtide (Myrcludex B) For research use only. Not for use in humans.

Bulevirtide (Myrcludex B)

Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport.

Amino-acid Sequence

Bulevirtide (Myrcludex B) Amino-acid Sequence

CAS No. 2012558-47-1

Selleck's Bulevirtide (Myrcludex B) has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.89%
99.89

Chemical Information & Solubility

Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (18.52 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 50 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Biological Activity

Description Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport.
Targets
NTCP
∼80 pM
In vitro
In vitro

Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt. transport.
Cell Research Cell lines U2OS cells
Concentrations 200 nM
Incubation Time 1 h
Method

Cells were treated with indicated concentration of drug for 1 h.

Product Information

Molecular Formula:

C248H355N65O72
Molecular Weight: 5398.86
CAS No.: 2012558-47-1
Appearance: White Powder
Peptide Content (by %N): ≥80%
Single Impurity (by HPLC): ≤1.0%
Assay (By Anhydrous, Acetic Acid-free): 95.0~105.0%
MS: Consistent
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt):		 3 years-20°C powder
Shipping: Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)