Home Metabolism CPT

CPT

Isoform-selective Products

CPT Products

  • All (4)
  • CPT Inhibitors (2)
  • CPT Activator (1)
  • CPT Agonist (1)
  • New CPT Products
Catalog No. Product Name Information Product Use Citations Product Validations
S8244 Etomoxir sodium salt Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.
Bioact Mater, 2024, 35:549-563
Cell Chem Biol, 2024, 31(10):1772-1786.e5
Oncogene, 2024, 43(6):406-419
S9819 C75 C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.
PLoS Pathog, 2024, 20(5):e1012228
Theranostics, 2023, 13(13):4482-4496
Theranostics, 2023, 10.7150/thno.84921
S6959 Perhexiline maleate Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).
Cancer Cell, 2022, S1535-6108(22)00312-9
S2269 Baicalin Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). Baicalin reduces the expression of NF-κB.
Ecotoxicol Environ Saf, 2024, 275:116262
Chem Biol Interact, 2024, 387:110820
Int J Mol Sci, 2023, 24(11)9435
S8244 Etomoxir sodium salt Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.
Bioact Mater, 2024, 35:549-563
Cell Chem Biol, 2024, 31(10):1772-1786.e5
Oncogene, 2024, 43(6):406-419
S6959 Perhexiline maleate Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).
Cancer Cell, 2022, S1535-6108(22)00312-9
S2269 Baicalin Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). Baicalin reduces the expression of NF-κB.
Ecotoxicol Environ Saf, 2024, 275:116262
Chem Biol Interact, 2024, 387:110820
Int J Mol Sci, 2023, 24(11)9435
S9819 C75 C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.
PLoS Pathog, 2024, 20(5):e1012228
Theranostics, 2023, 13(13):4482-4496
Theranostics, 2023, 10.7150/thno.84921

Choose Selective CPT Inhibitors

Tags: CPT inhibitor|CPT agonist|CPT activator|CPT inducer|CPT antagonist|CPT signaling pathway|CPT assay kit