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ACSS2 Products

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  • ACSS2 Inhibitors (4)
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Catalog No. Product Name Information Product Use Citations Product Validations
S8588 ACSS2 inhibitor ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV).
Nat Commun, 2024, 15(1):3200
Research (Wash D C), 2024, 7:0400
Cell Commun Signal, 2024, 22(1):187
E1931New AD-5584 AD-5584 is a specific inhibitor of human acyl-CoA synthetase short chain family member 2 (ACSS2). It significantly reduces lipid storage, decreases colony formation, and increases cell death in vitro, while also confirming blood-brain barrier (BBB) permeability.
E1147 VY-3-135 VY-3-135, a potent ACSS2 inhibitor with IC50 of 44 ± 3.85 nM, potently inhibits ACSS2 dependent fatty acid metabolism but has no effect on gene expression in tumors.
Cancers (Basel), 2024, 16(5)1035
E1211 MTB-9655 MTB-9655 is a novel, potent and selective Acetyl-Coenzyme A Synthetase 2 (ACSS2) inhibitor, which is currently in Phase I clinical investigation on patients with tumors with high levels of ACSS2.
S8588 ACSS2 inhibitor ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV).
Nat Commun, 2024, 15(1):3200
Research (Wash D C), 2024, 7:0400
Cell Commun Signal, 2024, 22(1):187
E1931New AD-5584 AD-5584 is a specific inhibitor of human acyl-CoA synthetase short chain family member 2 (ACSS2). It significantly reduces lipid storage, decreases colony formation, and increases cell death in vitro, while also confirming blood-brain barrier (BBB) permeability.
E1147 VY-3-135 VY-3-135, a potent ACSS2 inhibitor with IC50 of 44 ± 3.85 nM, potently inhibits ACSS2 dependent fatty acid metabolism but has no effect on gene expression in tumors.
Cancers (Basel), 2024, 16(5)1035
E1211 MTB-9655 MTB-9655 is a novel, potent and selective Acetyl-Coenzyme A Synthetase 2 (ACSS2) inhibitor, which is currently in Phase I clinical investigation on patients with tumors with high levels of ACSS2.
E1931New AD-5584 AD-5584 is a specific inhibitor of human acyl-CoA synthetase short chain family member 2 (ACSS2). It significantly reduces lipid storage, decreases colony formation, and increases cell death in vitro, while also confirming blood-brain barrier (BBB) permeability.

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Tags: ACSS2 inhibitor|ACSS2 agonist|ACSS2 activator|ACSS2 inducer|ACSS2 antagonist|ACSS2 signaling pathway|ACSS2 assay kit