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WDR5

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Catalog No. Product Name Information Product Use Citations Product Validations
S7833 OICR-9429 OICR-9429 is a potent antagonist of the interaction of WDR5 with peptide regions of MLL and Histone 3 and reduces viability of acute myeloid leukemia cells in vitro. It binds to WDR5 with high affinity (KD = 93 ± 28 nM.
PLoS Biol, 2024, 22(3):e3002240
iScience, 2024, 27(7):110187
J Clin Invest, 2023, 133(13)e169993
S2184 WDR5-0103 WDR5-0103 (WD-Repeat Protein 5-0103) is a small-molecule antagonist of WDR5 (WD40 repeat protein 5) with Kd of 450 nM.
J Clin Invest, 2023, 133(13)e169993
Cancer Res, 2023, 83(16):2750-2762
Cell Rep, 2023, 42(9):113145
S7833 OICR-9429 OICR-9429 is a potent antagonist of the interaction of WDR5 with peptide regions of MLL and Histone 3 and reduces viability of acute myeloid leukemia cells in vitro. It binds to WDR5 with high affinity (KD = 93 ± 28 nM.
PLoS Biol, 2024, 22(3):e3002240
iScience, 2024, 27(7):110187
J Clin Invest, 2023, 133(13)e169993
S2184 WDR5-0103 WDR5-0103 (WD-Repeat Protein 5-0103) is a small-molecule antagonist of WDR5 (WD40 repeat protein 5) with Kd of 450 nM.
J Clin Invest, 2023, 133(13)e169993
Cancer Res, 2023, 83(16):2750-2762
Cell Rep, 2023, 42(9):113145

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Tags: WDR5 inhibitor | WDR5 modulator | WDR5 inhibition | WDR5 regulation