STAT5 inhibitor | STAT5 inhibition

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S6784	STAT5-IN-1	STAT5-IN-1 is a potent and selective STAT5 inhibitor with IC50 of 47 μM for STAT5β isoform.	Selective	STAT5β, IC50: 47 μM
S0981	BD750	BD750 is an immunosuppressant and a dual inhibitor of JAK3 and STAT5 that inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation with IC50 of 1.5 μM and 1.1 μM for mouse and human T-cell proliferation, respectively.	Selective
S4358	Pimozide	Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.	Pan
S7337	SH-4-54	SH-4-54 is a potent STAT inhibitor with K_D of 300 nM and 464 nM for STAT3 and STAT5, respectively.	Pan	STAT5, Kd: 464 nM
S4182	Nifuroxazide	Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells.	Pan

STAT5 Selective Inhibitors