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PI4KIIIbeta Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S0041 UCB9608 UCB9608 (compound 44) is a potent, selective and orally bioavailable inhibitor of PI4KIIIβ with IC50 of 11 nM. UCB9608 is a potent immunosuppressive agent that improves metabolic stability and exhibits excellent pharmacokinetic profile. Selective PI4KIIIβ, IC50: 11 nM
S1489 PIK-93 PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM. Selective PI4KIIIβ, IC50: 19 nM
S6571 BQR695 BQR695 (NVP-BQR695) is a quinoxaline that displays sub-micromolar potency against human PI4KIIIβ (IC50~90 nM). Selective PI4KIIIβ, IC50: ~90 nM