Home Metabolism Acetyl-CoA carboxylase ACC1 Inhibitors
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ACC1 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8893 Firsocostat (GS-0976, ND-630) Firsocostat (GS-0976, ND-630) is a reversible inhibitor of acetyl CoA carboxylase (ACC) with IC50s of 2.1 nM,6.1 nM for hACC1 and hACC2,respectively. Pan hACC1, IC50: 2.1 nM
S8377 ND646 ND-646 is an allosteric inhibitor of the ACC (Acetyl-coA carboxylase) enzymes that prevents ACC subunit dimerization to suppress fatty acid synthesis with IC50 of 3.5 nM and 4.1 nM for hACC1 and hACC2, respectively. Pan hACC1, IC50: 3.5 nM
S6672 PF-05175157 PF-05175157 is a broad-spectrum effective ACC inhibitor with IC50 of 27.0 nM, 33.0 nM, 23.5 nM and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively. Pan hACC1, IC50: 27.0 nM