Kinase Inhibitor Library

Catalog No.L1200

A unique collection of 2011 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).

96 well plates

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Cited by 440 Publications

Description & Advantages

• A unique collection of 2011 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS)
 
• Targets kinases such as EGFR, PI3K, Aurora Kinase, CDK, and MEK
 
• Some inhibitors have been approved by the FDA
 
• Most are ATP competitive
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure and customer reviews
 
• NMR and HPLC validated to ensure high purity

Product Details

Formulation 1915 compounds pre-dissolved in 10mM DMSO, 32 compounds pre-dissolved in 10mM water, 62 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Kinase Inhibitor Library Composition

HTS Facility Partners