Home Biosimilar Antibodies Protein Tyrosine Kinase HER2 inhibitor Zanidatamab (Anti-HER2(ECD2&ECD4)) For research use only.
Not for use in humans.

Zanidatamab (Anti-HER2(ECD2&ECD4))

Synonyms: ZW25

Zanidatamab is a humanized bispecific IgG1 monoclonal antibody targeting two non-overlapping epitopes of HER2 (ECD2 and ECD4), with immunomodulating and antineoplastic activities. It has shown anti-tumor activity across various solid tumors with HER2 expression or amplification. M.W 148.28 kDa

Zanidatamab (Anti-HER2(ECD2&ECD4))

Purity & Quality Control

Choose Selective HER2 Inhibitors

Name Citation HER2 Others
Canertinib (CI-1033) 48 EGFR
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Sapitinib (AZD8931) 48 ErbB3,EGFR
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Mubritinib (TAK 165) 39
AEE788 (NVP-AEE788) 13 EGFR,c-Abl,FLT1
AC480 (BMS-599626) 10 HER1,HER4
TAK-285 4 EGFR/HER1,HER4,MEK1
Tyrphostin AG 879 3 Trk
Tuxobertinib (BDTX-189) 2 EGFR,RIPK2,BLK
Epertinib hydrochloride 0 EGFR,HER4
TAS0728 1
Tyrphostin AG-528 0 EGFR
SU5204 1 VEGFR-2
Pyrotinib dimaleate 4 EGFR
Poziotinib 34 HER1,HER4
HER2-Inhibitor-1
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EGCG ((-)-Epigallocatechin Gallate) FASN,EGFR,DNMT
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Zanidatamab is a humanized bispecific IgG1 monoclonal antibody targeting two non-overlapping epitopes of HER2 (ECD2 and ECD4), with immunomodulating and antineoplastic activities. It has shown anti-tumor activity across various solid tumors with HER2 expression or amplification. M.W 148.28 kDa

Product Details

CAS No. 2169946-15-8
Source CHO
Storage
(From the date of receipt)		 -80℃

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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