Home Biosimilar Antibodies Protein Tyrosine Kinase HER2 null Trastuzumab MMAE For research use only.
Not for use in humans.

Trastuzumab MMAE

Trastuzumab MMAE is an antibody-drug conjugate (ADC). It is composed of monomethyl auristatin E (MMAE) and trastuzumab conjugated via a Vc (Valine‐citrulline) linker. Trastuzumab MMAE has high affinity, specificity and anti-tumor activity in vitro.

Trastuzumab MMAE

CAS No.

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Purity & Quality Control

Batch: D405201 Purity: 98% Protein concentration: 3.15mg/ml Endotoxin Level: ＜1EU/mg
98

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Name Citation HER2 Others
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Mubritinib (TAK 165) 38
AEE788 (NVP-AEE788) 13 EGFR,c-Abl,FLT1
AC480 (BMS-599626) 10 HER1,HER4
TAK-285 4 EGFR/HER1,HER4,MEK1
Tyrphostin AG 879 3 Trk
Poziotinib 33 HER1,HER4
HER2-Inhibitor-1
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Trastuzumab MMAE is an antibody-drug conjugate (ADC). It is composed of monomethyl auristatin E (MMAE) and trastuzumab conjugated via a Vc (Valine‐citrulline) linker. Trastuzumab MMAE has high affinity, specificity and anti-tumor activity in vitro.

Product Details

ADC antiody Trastuzumab
ADC linker Vc linker
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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