Talquetamab (Anti-GPRC5D)

Synonyms: JNJ-64407564

Talquetamab (Anti-GPRC5D) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab exhibits antitumor activity. MW: 145.5 KD.

Talquetamab (Anti-GPRC5D)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 5.63mg/ml Endotoxin Level: <1EU/mg
99

Choose Selective GPR Inhibitors

Name Citation GPR
AZD1981 1
OC000459 0
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Talquetamab (Anti-GPRC5D) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab exhibits antitumor activity. MW: 145.5 KD.

Product Details

CAS No. 2226212-40-2
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac,pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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