Home Biosimilar Antibodies Protein Tyrosine Kinase HER2 antibody Seribantumab (Anti-ERBB3 / HER3) For research use only.
Not for use in humans.

Seribantumab (Anti-ERBB3 / HER3)

Synonyms: MM 121

Seribantumab (Anti-ERBB3 / HER3) is a fully human IgG2 monoclonal antibody that targets HER3. It inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. MW : 143.14 KD.

Seribantumab (Anti-ERBB3 / HER3)

Purity & Quality Control

Batch: A266001 Purity: 99% Protein concentration: 14.36mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective HER2 Inhibitors

Name Citation HER2 Others
Canertinib (CI-1033) 46 EGFR
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Mubritinib (TAK 165) 38
AEE788 (NVP-AEE788) 13 EGFR,c-Abl,FLT1
AC480 (BMS-599626) 10 HER1,HER4
TAK-285 4 EGFR/HER1,HER4,MEK1
Tyrphostin AG 879 3 Trk
Poziotinib 33 HER1,HER4
HER2-Inhibitor-1
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Seribantumab (Anti-ERBB3 / HER3) is a fully human IgG2 monoclonal antibody that targets HER3. It inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. MW : 143.14 KD.

Product Details

CAS No. 1334296-12-6
Molecular Weight 143.14
Isotype Human IgG2SA
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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