Semaglutide Sodium

Synonyms: Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217

Semaglutide Sodium (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), a long-acting glucagon-like peptide 1 (GLP-1) analogue, is a GLP-1 receptor agonist with the potential for the treatment of type 2 diabetes mellitus (T2DM).

Semaglutide Sodium Chemical Structure

Semaglutide Sodium Chemical Structure

CAS No. 910463-68-2(free base)

Purity & Quality Control

Semaglutide Sodium Related Products

Biological Activity

Description Semaglutide Sodium (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), a long-acting glucagon-like peptide 1 (GLP-1) analogue, is a GLP-1 receptor agonist with the potential for the treatment of type 2 diabetes mellitus (T2DM).
Targets
GLP-1 receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05714683 Not yet recruiting
Diabetes Mellitus Type 2
Novo Nordisk A/S
December 31 2024 --
NCT05689372 Not yet recruiting
Diabetes Mellitus Type 2
Novo Nordisk A/S
June 30 2024 --
NCT06015893 Recruiting
Addiction|Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)|National Institutes of Health Clinical Center (CC)
May 15 2024 Phase 2

Chemical Information & Solubility

Molecular Weight 4113.58(free base) Formula

C187H291N45O59

CAS No. 910463-68-2(free base) SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

4-Methylpyridine : 4 mg/mL

Water : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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