Home Cytoskeletal Signaling Kinesin inhibitor SB-743921 For research use only.

SB-743921

Synonyms: SB-921

SB-743921 (SB-921) is an inhibitor of Kinesin Spindle Protein (KSP), a mitotic protein essential for cell cycle control and motility. It functions by selectively targeting rapidly dividing cells and disrupting spindle formation during cell division, leading to G2/M phase arrest and ultimately causing cell death. It also inhibits proliferation and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cell lines.

SB-743921 Chemical Structure

SB-743921 Chemical Structure

CAS No. 618430-39-0

Purity & Quality Control

SB-743921 Related Products

Signaling Pathway

Kinesin Signaling Pathways

Kinesin Signaling Pathway

Biological Activity

Description SB-743921 (SB-921) is an inhibitor of Kinesin Spindle Protein (KSP), a mitotic protein essential for cell cycle control and motility. It functions by selectively targeting rapidly dividing cells and disrupting spindle formation during cell division, leading to G2/M phase arrest and ultimately causing cell death. It also inhibits proliferation and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cell lines.

Chemical Information & Solubility

Molecular Weight 553.52 Formula

C31H33ClN2O3.ClH
CAS No. 618430-39-0 SDF Download SB-743921 SDF
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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