Roxatidine Acetate HCl

Synonyms: HOE 760

Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.

Roxatidine Acetate HCl Chemical Structure

Roxatidine Acetate HCl Chemical Structure

CAS No. 93793-83-0

Purity & Quality Control

Batch: S188001 DMSO]77 mg/mL]false]Water]77 mg/mL]false]Ethanol]12 mg/mL]false Purity: 99.48%
99.48

Roxatidine Acetate HCl Related Products

Biological Activity

Description Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.
Targets
Histamine H2 receptor [1]
3.2 μM

Chemical Information & Solubility

Molecular Weight 384.9 Formula

C19H28N2O4.HCl

CAS No. 93793-83-0 SDF Download Roxatidine Acetate HCl SDF
Smiles CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 77 mg/mL ( (200.05 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 77 mg/mL

Ethanol : 12 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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