Home Neuronal Signaling Histamine Receptor antagonist Ranitidine For research use only.

Ranitidine

Synonyms: AH-19065

Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.

Ranitidine Chemical Structure

Ranitidine Chemical Structure

CAS No. 66357-35-5

Purity & Quality Control

Batch: S566201 DMSO]63 mg/mL]false]]]false]]]false Purity: 98%
98

Ranitidine Related Products

Signaling Pathway

Histamine Receptor Signaling Pathways

Histamine Receptor Signaling Pathway

Biological Activity

Description Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05399927 Completed
Music Therapy|Cardiovascular Diseases|Critical Care|Emergencies
Universidad Miguel Hernandez de Elche
 July 2015 Not Applicable
NCT01539655 Completed
Medullary Thyroid Cancer
Sanofi
 February 2012 Phase 1
NCT01017198 Completed
Advanced Solid Tumors
Biogen
 November 2009 Phase 1

Chemical Information & Solubility

Molecular Weight 314.40 Formula

C13H22N4O3S
CAS No. 66357-35-5 SDF --
Smiles CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 63 mg/mL ( (200.38 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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