Home Biosimilar Antibodies Protein Tyrosine Kinase HER2 null Patritumab (Anti-ERBB3 / HER3) For research use only.
Not for use in humans.

Patritumab (Anti-ERBB3 / HER3)

Synonyms: Human Anti-ERBB3 Recombinant Antibody

Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab, potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD.

Patritumab (Anti-ERBB3 / HER3)

Click to purchase the isotype control of Patritumab (Anti-ERBB3 / HER3)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 13.58mg/ml Endotoxin Level: ＜1EU/mg
99

Choose Selective HER2 Inhibitors

Name Citation HER2 Others
Canertinib (CI-1033) 46 EGFR
CP-724714 108
Sapitinib (AZD8931) 46 ErbB3,EGFR
CUDC-101 22 EGFR,HDAC,HDAC1
Mubritinib (TAK 165) 38
AEE788 (NVP-AEE788) 13 EGFR,c-Abl,FLT1
AC480 (BMS-599626) 10 HER1,HER4
TAK-285 4 EGFR/HER1,HER4,MEK1
Tyrphostin AG 879 3 Trk
Poziotinib 33 HER1,HER4
HER2-Inhibitor-1
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab, potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD.

Product Details

CAS No. 1262787-83-6
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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