Home GPCR & G Protein MT Receptor antagonist Luzindole For research use only.

Luzindole

Synonyms: N-0774

Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.

Luzindole Chemical Structure

Luzindole Chemical Structure

CAS No. 117946-91-5

Purity & Quality Control

Batch: S358401 DMSO]58 mg/mL]false]Ethanol]58 mg/mL]false]Water]Insoluble]false Purity: 99.47%
99.47

Luzindole Related Products

Signaling Pathway

MT Receptor Signaling Pathways

MT Receptor Signaling Pathway

Biological Activity

Description Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.
Targets
MT2 [1] MT1 [1]
7.3 nM(Ki) 179 nM(Ki)

Chemical Information & Solubility

Molecular Weight 292.37 Formula

C19H20N2O
CAS No. 117946-91-5 SDF --
Smiles CC(=O)NCCC1=C(CC2=CC=CC=C2)[NH]C3=CC=CC=C13
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 58 mg/mL ( (198.37 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 58 mg/mL

Water : Insoluble


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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