Labetuzumab govitecan

Synonyms: IMMU-130

Labetuzumab govitecan (IMMU-135) is a humanised anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody linked site-specifically to the active metabolite of irinotecan SN-38 via a proprietary linker. Labetuzumab govitecan can be used for research on colorectal cancer.

Labetuzumab govitecan

CAS No. 1469876-18-3

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Purity & Quality Control

Batch: D404801 Purity: 99% Protein concentration: 4.91 mg/ml Endotoxin Level: <1EU/mg
99

Choose Selective Antibody-Drug Conjugate Inhibitors

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Labetuzumab govitecan (IMMU-135) is a humanised anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody linked site-specifically to the active metabolite of irinotecan SN-38 via a proprietary linker. Labetuzumab govitecan can be used for research on colorectal cancer.

Product Details

CAS No. 1469876-18-3
ADC antiody Labetuzumab
ADC linker Lysine; a maleimide-type cleavable linker
ADC cytotoxin SN-38
Formulation 1xPBS
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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