Home PI3K/Akt/mTOR mTOR activator L-Leucine For research use only.

L-Leucine

Synonyms: (S)-Leucine, Leu

Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.

L-Leucine Chemical Structure

L-Leucine Chemical Structure

CAS No. 61-90-5

Purity & Quality Control

L-Leucine Related Products

Signaling Pathway

mTOR Signaling Pathways

mTOR Signaling Pathway

Biological Activity

Description Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
In vitro
In vitro Leucine also stimulates protein synthesis in muscle and is closely associated with the release of gluconeogenic precursors, such as alanine, from muscle[1].
In Vivo
In vivo Leucine has a half-life of 45 minutes[1].
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Chemical Information & Solubility

Molecular Weight 131.17 Formula

C6H13NO2
CAS No. 61-90-5 SDF --
Smiles CC(C)CC(C(=O)O)N
Storage (From the date of receipt)

In vitro
Batch:

Water : 13 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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