Dexamethasone phosphate disodium

Synonyms: DEX, Dexamethasone 21-phosphate disodium salt

Dexamethasone phosphate disodium is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.

Dexamethasone phosphate disodium Chemical Structure

Dexamethasone phosphate disodium Chemical Structure

CAS No. 2392-39-4

Purity & Quality Control

Batch: S595601 Water]100 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.98%
99.98

Dexamethasone phosphate disodium Related Products

Biological Activity

Description Dexamethasone phosphate disodium is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.
Targets
glucocorticoid receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05935293 Not yet recruiting
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Eduardo Schiffer|University Hospital Geneva
December 1 2024 Phase 4
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MED-EL Elektromedizinische Geräte GesmbH
June 30 2024 Not Applicable
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Relapsed and/or Refractory Multiple Myeloma
Adriana Rossi|Icahn School of Medicine at Mount Sinai
June 3 2024 Phase 1|Phase 2

Chemical Information & Solubility

Molecular Weight 516.4 Formula

C22H28FNa2O8P

CAS No. 2392-39-4 SDF --
Smiles [Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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