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Datopotamab deruxtecan
Synonyms: DS-1062, DS-1062A, Anti-TRP2/dxd
Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC.
CAS No. 2238831-60-0
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Purity & Quality Control
Batch:
Purity:
99%
Protein concentration: 7.195mg/ml
Endotoxin Level: ＜1EU/mg
99
Choose Selective Antibody-Drug Conjugate Inhibitors
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Biological Activity
| Description | Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC. |
|---|
Product Details
| CAS No. | 2238831-60-0 |
|---|---|
| DAR | 4.2 |
| ADC antiody | Datopotamab |
| ADC linker | A tetrapeptide-based linker |
| ADC cytotoxin | Dxd |
| Formulation | 1xPBS |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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