Home Neuronal Signaling Histamine Receptor antagonist Cyclizine For research use only.

Cyclizine

Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.

Cyclizine Chemical Structure

Cyclizine Chemical Structure

CAS No. 82-92-8

Purity & Quality Control

Batch: S089701 DMSO]53 mg/mL]false]Ethanol]53 mg/mL]false]Water]Insoluble]false Purity: 99.43%
99.43

Cyclizine Related Products

Signaling Pathway

Histamine Receptor Signaling Pathways

Histamine Receptor Signaling Pathway

Biological Activity

Description Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.
Targets
histamine H1 receptor [1]

Chemical Information & Solubility

Molecular Weight 266.38 Formula

C18H22N2
CAS No. 82-92-8 SDF --
Smiles CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 53 mg/mL ( (198.96 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 53 mg/mL

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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