Home Protein Tyrosine Kinase Syk inhibitor Cevidoplenib dimesylate For research use only.

Cevidoplenib dimesylate

Synonyms: SKI-O-703 dimesylate

Cevidoplenib dimesylate(SKI-O-703 dimesylate) is an orally available inhibitor of spleen tyrosine kinase (Syk) with potential anti-inflammatory and immunomodulating activities. It attenuates the progression of autoantibody-mediated autoimmune diseases by inhibiting both autoantibody-producing and autoantibody-sensing cells.

Cevidoplenib dimesylate Chemical Structure

Cevidoplenib dimesylate Chemical Structure

CAS No. 2043659-93-2

Purity & Quality Control

Batch: E183601 DMSO]100 mg/mL]false]Water]12 mg/mL]false]Ethanol]Insoluble]false Purity: 97.49%
97.49

Cevidoplenib dimesylate Related Products

Signaling Pathway

Syk Signaling Pathways

Syk Signaling Pathway

Biological Activity

Description Cevidoplenib dimesylate(SKI-O-703 dimesylate) is an orally available inhibitor of spleen tyrosine kinase (Syk) with potential anti-inflammatory and immunomodulating activities. It attenuates the progression of autoantibody-mediated autoimmune diseases by inhibiting both autoantibody-producing and autoantibody-sensing cells.

Chemical Information & Solubility

Molecular Weight 665.74 Formula

C25H27N7O3.2CH4O3S
CAS No. 2043659-93-2 SDF Download Cevidoplenib dimesylate SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (150.2 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 12 mg/mL

Ethanol : Insoluble


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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