1-Cyclohexyl-3-dodecyl urea

Synonyms: CDU, N-Cyclohexyl-N-dodecyl urea, NCND

1-Cyclohexyl-3-dodecyl urea (CDU, N-Cyclohexyl-N-dodecyl urea, NCND) is a highly selective inhibitor of soluble epoxide hydrolase (sEH) that increases epoxyeicosatrienoic acids (EETs) levels.

1-Cyclohexyl-3-dodecyl urea Chemical Structure

1-Cyclohexyl-3-dodecyl urea Chemical Structure

CAS No. 402939-18-8

Purity & Quality Control

Batch: S054801 Ethanol]30 mg/mL]false]DMSO]Insoluble]false]Water]Insoluble]false Purity: 99.55%
99.55

1-Cyclohexyl-3-dodecyl urea Related Products

Biological Activity

Description 1-Cyclohexyl-3-dodecyl urea (CDU, N-Cyclohexyl-N-dodecyl urea, NCND) is a highly selective inhibitor of soluble epoxide hydrolase (sEH) that increases epoxyeicosatrienoic acids (EETs) levels.
Targets
sEH [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
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Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
March 4 2022 --
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Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
November 29 2021 --
NCT05687006 Completed
Mammaplasty
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NCT04329182 Unknown status
Active Sacroiliitis in Ankylosing Spondylitis
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Synovitis of Knee|Osteoarthritis Knee
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Chemical Information & Solubility

Molecular Weight 310.52 Formula

C19H38N2O

CAS No. 402939-18-8 SDF --
Smiles CCCCCCCCCCCCNC(=O)NC1CCCCC1
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Ethanol : 30 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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