Home GPCR & G Protein NPY receptor antagonist BIBO 3304 Trifluoroacetate For research use only.

BIBO 3304 Trifluoroacetate

Synonyms: BIBO-3304 TFA

BIBO 3304 Trifluoroacetate (BIBO-3304 TFA) is a novel neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 values of 0.38 nM and 0.72 nM for human Y1 receptor and rat Y1 receptor, respectively. BIBO 3304 shows low affinity for the human Y2 receptor, human and rat Y4 receptor as well as for the human and rat Y5 receptor (IC50 values >1000 nM).

BIBO 3304 Trifluoroacetate Chemical Structure

BIBO 3304 Trifluoroacetate Chemical Structure

CAS No. 191868-14-1

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BIBO 3304 Trifluoroacetate Related Products

Biological Activity

Description

BIBO 3304 Trifluoroacetate (BIBO-3304 TFA) is a novel neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 values of 0.38 nM and 0.72 nM for human Y1 receptor and rat Y1 receptor, respectively. BIBO 3304 shows low affinity for the human Y2 receptor, human and rat Y4 receptor as well as for the human and rat Y5 receptor (IC50 values >1000 nM).
Targets
human Y1 receptor [1] rat Y1 receptor [1]
0.38 nM 0.72 nM

Chemical Information & Solubility

Molecular Weight 643.66 Formula

C31H36F3N7O5
CAS No. 191868-14-1 SDF --
Smiles NC(=N)NCCCC(NC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2)C(=O)NCC3=CC=C(CNC(N)=O)C=C3.OC(=O)C(F)(F)F
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (155.36 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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