Home Biosimilar Antibodies Others Others antibody Anti-Hepcidin / HAMP For research use only.
Not for use in humans.

Anti-Hepcidin / HAMP

Synonyms: LY2787106

Anti-Hepcidin / HAMP (LY2787106) is a fully humanized monoclonal antibody againsts hepcidin. It is currently in phase I human trials for cancer-related anemia. It binds to hepcidin and prevents its binding to the iron exporting protein ferroportin and prevents hepcidin-induced internalization and degradation of ferroportin and increases ferroportin-mediated iron export. MW: 145.5 KD.

Anti-Hepcidin / HAMP

Purity & Quality Control

Biological Activity

Description Anti-Hepcidin / HAMP (LY2787106) is a fully humanized monoclonal antibody againsts hepcidin. It is currently in phase I human trials for cancer-related anemia. It binds to hepcidin and prevents its binding to the iron exporting protein ferroportin and prevents hepcidin-induced internalization and degradation of ferroportin and increases ferroportin-mediated iron export. MW: 145.5 KD.

Product Details

Molecular Weight 145.5 kDa
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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