Home Transmembrane Transporters Potassium Channel inhibitor Glipizide For research use only.

Glipizide

Synonyms: CP-28720,K 4024

Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.

Glipizide Chemical Structure

Glipizide Chemical Structure

CAS No. 29094-61-9

Purity & Quality Control

Glipizide Related Products

Signaling Pathway

Potassium Channel Signaling Pathways

Potassium Channel Signaling Pathway

Biological Activity

Description Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06168812 Recruiting
Pancreatic Cancer|Pancreatic Carcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer Metastatic|Metastatic Pancreatic Cancer|Metastatic Pancreatic Ductal Adenocarcinoma
Memorial Sloan Kettering Cancer Center
 December 5 2023 Phase 2
NCT00509236 Completed
Diabetes Mellitus Type 2|End-Stage Kidney Disease
Merck Sharp & Dohme LLC
 October 19 2007 Phase 3

Chemical Information & Solubility

Molecular Weight 445.54 Formula

C21H27N5O4S
CAS No. 29094-61-9 SDF Download Glipizide SDF
Smiles CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 89 mg/mL ( (199.75 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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