Choose Your Country or Region

Retatrutide

Catalog No.P1230 Purity: 99.72%

Retatrutide (LY3437943) acts as a triple agonist peptide of the glucagon receptor (GCGR), glucagon-like peptide-1 receptor (GLP-1R) and glucosedependent insulinotropic polypeptide receptor (GIPR). Retatrutide binds to human GCGR, GLP-1R, and GIPR with EC50 values of 5.79, 0.775 nM, and 0.0643, respectively. Retatrutide has the potential for use in research on obesity.

Amino-acid Sequence

CAS No. 2381089-83-2

Purity & Quality Control

Batch: P123001 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false Purity: 99.72%

99.72

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( ； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Retatrutide (LY3437943) acts as a triple agonist peptide of the glucagon receptor (GCGR), glucagon-like peptide-1 receptor (GLP-1R) and glucosedependent insulinotropic polypeptide receptor (GIPR). Retatrutide binds to human GCGR, GLP-1R, and GIPR with EC50 values of 5.79, 0.775 nM, and 0.0643, respectively. Retatrutide has the potential for use in research on obesity.

References

[1] Coskun T, et al. Cell Metab. 2022 Sep 6;34(9):1234-1247.e9.

Product Information

Molecular Formula:	C₂₂₁H₃₄₂N₄₆O₆₈
CAS No.:	2381089-83-2
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)