Proteinase K is a serine endoprotease, is used for isolating amyloid cores and is effective over a wide pH range (4–12), including in the presence of SDS or urea. It is commonly used as a preparative reagent for destruction of proteins, including DNAses and RNAses, in DNA and RNA preparations.

Amino-acid Sequence

CAS No. 39450-01-6

Purity & Quality Control

Batch: P124201 DMSO] 57 mg/mL] false] Water] 57 mg/mL] false] Ethanol] Insoluble] false Purity: 98.54%

98.54

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 57 mg/mL ( ； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 57 mg/mL

Ethanol : Insoluble

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In vivo
Batch:

Add solvents to the product individually and in order.

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Biological Activity

Description	Proteinase K is a serine endoprotease, is used for isolating amyloid cores and is effective over a wide pH range (4–12), including in the presence of SDS or urea. It is commonly used as a preparative reagent for destruction of proteins, including DNAses and RNAses, in DNA and RNA preparations.

References
[1] Kushnirov VV, et al. Prion. 2020 Dec;14(1):11-19.

References

[1] Kushnirov VV, et al. Prion. 2020 Dec;14(1):11-19.

Product Information

CAS No.:	39450-01-6
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)