Pasireotide

Pasireotide (SOM230) is a multi-receptor ligand somatostatin analogue with high binding affinity for somatostatin receptor (SSTR) subtypes sst1,2,3 and sst5. It potently suppresses GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing’s disease.

Amino-acid Sequence

Pasireotide Amino-acid Sequence

CAS No. 396091-73-9

Purity & Quality Control

Batch: P112701 DMSO] 100 mg/mL] false] Ethanol] 100 mg/mL] false] Water] Insoluble] false Purity: 99.47%
99.47

Chemical Information & Solubility

Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (95.49 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 100 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Biological Activity

Description Pasireotide (SOM230) is a multi-receptor ligand somatostatin analogue with high binding affinity for somatostatin receptor (SSTR) subtypes sst1,2,3 and sst5. It potently suppresses GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing’s disease.
Targets
SST2
9

Product Information

Molecular Formula:

C58H66N10O9

Molecular Weight: 1047.21
CAS No.: 396091-73-9
Appearance: White Powder
Peptide Content (by %N): ≥80%
Single Impurity (by HPLC): ≤1.0%
Assay (By Anhydrous, Acetic Acid-free): 95.0~105.0%
MS: Consistent
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt):
3 years-20°C powder
Shipping: Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)