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ODN 1826 sodium (CpG 1826 sodium)

Cat.No.P1246

ODN 1826 sodium (CpG 1826 sodium) is a synthetic CpG oligodeoxynucleotide and agonist of TLR9 signaling pathway, that induces G1-phase arrest and apoptosis in A20 lymphoma cells while stimulating NO and iNOS production in mouse models, as part of its immunostimulatory activity.

ODN 1826 sodium (CpG 1826 sodium) Chemical Structure

CAS No.

Quality Control

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vivo
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Biological Activity

Description	ODN 1826 sodium (CpG 1826 sodium) is a synthetic CpG oligodeoxynucleotide and agonist of TLR9 signaling pathway, that induces G1-phase arrest and apoptosis in A20 lymphoma cells while stimulating NO and iNOS production in mouse models, as part of its immunostimulatory activity.
Targets/IC₅₀/Ki	TLR9

References
https://pubmed.ncbi.nlm.nih.gov/23357786/ https://pubmed.ncbi.nlm.nih.gov/12067301/

References

https://pubmed.ncbi.nlm.nih.gov/23357786/
https://pubmed.ncbi.nlm.nih.gov/12067301/

Product Information

Molecular Weight	6804
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)