Home Peptide Products gp91ds-tat For research use only. Not for use in humans.

gp91ds-tat

gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.

Amino-acid Sequence

gp91ds-tat Amino-acid Sequence

CAS No.

Purity & Quality Control

Batch: P121301 Water] 49 mg/mL] false] ] ] false] ] ] false Purity: 99.95%
99.95

Chemical Information & Solubility

Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

Water : 49 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Biological Activity

Description gp91ds-tat, a peptide inhibitor for NADPH oxidase assembly, is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. The tat sequence facilitates the entry of this peptide into cells.
Targets
NADPH oxidase
In vitro
In vitro

Gp91ds-tat, an inhibitor of NOX (NADPH oxidase) 2, can prevented high extracellular glucose (Hi-Glu)/Thiamet G (ThmG)-induced ROS generation.[2]
In Vivo
In vivo

Gp91ds-tat can attenuate cerebral I/R injury in a rat model of middle cerebral artery occlusion (MCAO) through reducing ROS levels, inhibiting neuronal apoptosis and degeneration, and alleviating BBB damage.[3]
Animal Research Animal Models middle cerebral artery occlusion (MCAO) model rats
Dosages 100 ng/kg
Administration infused into the ventricle

Product Information

Molecular Formula:

C109H202N52O25S1
Molecular Weight: 2673.3
Appearance: White Powder
Peptide Content (by %N): ≥80%
Single Impurity (by HPLC): ≤1.0%
Assay (By Anhydrous, Acetic Acid-free): 95.0~105.0%
MS: Consistent
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt):		 3 years-20°C powder
Shipping: Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)