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Etanercept

Catalog No.P1240

Etanercept, a dimeric fusion protein, functions as an inhibitor of TNF by binding to TNF. It competitively blocks the attachment of both TNF-α and TNF-β to their cell surface receptors, thereby neutralizing TNF's biological activity. Etanercept has proven effectiveness in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.

Amino-acid Sequence

CAS No. 185243-69-0

Purity & Quality Control

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vivo
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Biological Activity

Description	Etanercept, a dimeric fusion protein, functions as an inhibitor of TNF by binding to TNF. It competitively blocks the attachment of both TNF-α and TNF-β to their cell surface receptors, thereby neutralizing TNF's biological activity. Etanercept has proven effectiveness in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.

References

Product Information

CAS No.:	185243-69-0
Storage (From the date of receipt):	2 years -20°C liquid
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)