Disitertide(P144)

Catalog No.P1218 Purity: 98.38%

Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor, is also a PI3K inhibitor and an apoptosis inducer.

Amino-acid Sequence

CAS No. 272105-42-7

Purity & Quality Control

Batch: P121801 DMSO] 25 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 98.38%

98.38

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 25 mg/mL ( (15.81 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description

Targets

TGF-β1	PI3K

References
[1] Qiu SS, et al. PLoS One. 2015 Dec 31;10(12):e0144489. [2] Yang J, et al. Int J Mol Med. 2019 May;43(5):2212-2220.

References

Product Information

Molecular Formula:	C₆₈H₁₀₉N₁₇O₂₂S₂
Molecular Weight:	1580.83
CAS No.:	272105-42-7
Appearance:	White Powder
Peptide Content (by %N):	≥80%
Single Impurity (by HPLC):	≤1.0%
Assay (By Anhydrous, Acetic Acid-free):	95.0~105.0%
MS:	Consistent
Packing:	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt):	3 years-20°C powder
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)