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NOD Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S2863 Nodinitib-1 (ML130) Nodinitib-1(ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2.
Cells, 2023, 12(5)696
J Neuroinflammation, 2020, 17(1):364
J Immunol, 2020, 205(3):811-821
S0004 NOD-IN-1 NOD-IN-1 (MDK19922, Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptor 1 (NOD1) and NOD2 with IC50 of 5.74 μM and 6.45 μM, respectively.
PLoS Pathog, 2023, 19(6):e1011455
S0349 Inarigivir soproxil Inarigivir soproxil (GS 9992, SB 9200) is an oral agonist of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. Inarigivir soproxil has broad-spectrum antiviral activity against RNA viruses with EC50 of 2.2 μM and 1.0 μM for HCV 1a and HCV 1b.
S2863 Nodinitib-1 (ML130) Nodinitib-1(ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2.
Cells, 2023, 12(5)696
J Neuroinflammation, 2020, 17(1):364
J Immunol, 2020, 205(3):811-821
S0004 NOD-IN-1 NOD-IN-1 (MDK19922, Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptor 1 (NOD1) and NOD2 with IC50 of 5.74 μM and 6.45 μM, respectively.
PLoS Pathog, 2023, 19(6):e1011455
S0349 Inarigivir soproxil Inarigivir soproxil (GS 9992, SB 9200) is an oral agonist of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. Inarigivir soproxil has broad-spectrum antiviral activity against RNA viruses with EC50 of 2.2 μM and 1.0 μM for HCV 1a and HCV 1b.

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