Home Cytoskeletal Signaling Cardiac Myosin

Cardiac Myosin

Cardiac Myosin Products

  • All (3)
  • Cardiac Myosin Inhibitors (2)
  • Cardiac Myosin Activator (1)
  • New Cardiac Myosin Products
Catalog No. Product Name Information Product Use Citations Product Validations
S9948 Danicamtiv (MYK-491)

Danicamtiv (MYK-491, SAR 440181) is a novel cardiac myosin activator that enhances cardiomyocyte contraction.
bioRxiv, 2024, 2024.10.09.617269
J Am Heart Assoc, 2023, 12(20):e030682
E4662New CK-586 CK-586(CK-4021586) is an inhibitor of cardiac myosin used to treat obstructive hypertrophic cardiomyopathy (oHCM). It effectively reduces left ventricular outflow tract obstruction (LVOTO) in a dose-dependent manner.
E1016 Aficamten (CK-274)

Aficamten (CK-274, CK 3773274) is a novel cardiac myosin inhibitor that reduces myocardial contractility in vitro and in vivo with an IC50 of 1.4 μM.
E4662New CK-586 CK-586(CK-4021586) is an inhibitor of cardiac myosin used to treat obstructive hypertrophic cardiomyopathy (oHCM). It effectively reduces left ventricular outflow tract obstruction (LVOTO) in a dose-dependent manner.
E1016 Aficamten (CK-274)

Aficamten (CK-274, CK 3773274) is a novel cardiac myosin inhibitor that reduces myocardial contractility in vitro and in vivo with an IC50 of 1.4 μM.
S9948 Danicamtiv (MYK-491)

Danicamtiv (MYK-491, SAR 440181) is a novel cardiac myosin activator that enhances cardiomyocyte contraction.
bioRxiv, 2024, 2024.10.09.617269
J Am Heart Assoc, 2023, 12(20):e030682
E4662New CK-586 CK-586(CK-4021586) is an inhibitor of cardiac myosin used to treat obstructive hypertrophic cardiomyopathy (oHCM). It effectively reduces left ventricular outflow tract obstruction (LVOTO) in a dose-dependent manner.

Choose Selective Cardiac Myosin Inhibitors

Tags: Cardiac Myosin inhibitor|Cardiac Myosin agonist|Cardiac Myosin activator|Cardiac Myosin inducer|Cardiac Myosin antagonist|Cardiac Myosin signaling pathway|Cardiac Myosin assay kit