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High-mobility Group

Isoform-selective Products

HMGB

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High-mobility Group Inhibitors (2)
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Catalog No.	Product Name	Information	Product Use Citations	Product Validations
S2302	Glycyrrhizin (NSC 167409)	Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).	Cell Mol Life Sci, 2024, 81(1):408 Ecotoxicol Environ Saf, 2024, 272:116068 Front Immunol, 2023, 14:1024706
S2376	Ammonium Glycyrrhizinate	Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. Ammonium glycyrrhizinate is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses. Ammonium Glycyrrhizinate also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.	Eur J Pharmacol, 2024, 962:176171 Pharmacol Res, 2023, 192:106791 Food Funct, 2022, 10.1039/d2fo02337g
S2302	Glycyrrhizin (NSC 167409)	Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).	Cell Mol Life Sci, 2024, 81(1):408 Ecotoxicol Environ Saf, 2024, 272:116068 Front Immunol, 2023, 14:1024706
S2376	Ammonium Glycyrrhizinate	Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. Ammonium glycyrrhizinate is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses. Ammonium Glycyrrhizinate also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.	Eur J Pharmacol, 2024, 962:176171 Pharmacol Res, 2023, 192:106791 Food Funct, 2022, 10.1039/d2fo02337g

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Tags: High-mobility Group inhibitor|High-mobility Group agonist|High-mobility Group activator|High-mobility Group inducer|High-mobility Group antagonist|High-mobility Group signaling pathway|High-mobility Group assay kit