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GRK Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S8489 GSK180736A (GSK180736) GSK180736A (GSK180736), developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1); ≥400-fold selective for GRK2 over both GRK1 and GRK5.
Cell Rep, 2023, 42(7):112812
Cancer Lett, 2022, 529:112-125
E2817 GRK5-IN-2 GRK5-IN-2 is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.
S6621 CCG215022 CCG215022 serves as a pan-G protein-coupled receptor kinases (GRKs) inhibitor with IC50 of 3.9 μM, 0.15 μM, 0.38 μM for GRK1, GRK2, GRK5, respectively.
ACS Omega, 2024, 9(37):38477-38489
S8489 GSK180736A (GSK180736) GSK180736A (GSK180736), developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1); ≥400-fold selective for GRK2 over both GRK1 and GRK5.
Cell Rep, 2023, 42(7):112812
Cancer Lett, 2022, 529:112-125
E2817 GRK5-IN-2 GRK5-IN-2 is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.
S6621 CCG215022 CCG215022 serves as a pan-G protein-coupled receptor kinases (GRKs) inhibitor with IC50 of 3.9 μM, 0.15 μM, 0.38 μM for GRK1, GRK2, GRK5, respectively.
ACS Omega, 2024, 9(37):38477-38489

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Tags: GRK antibodies| GRK antagonist | GRK inhibitor |  GRK agonist |  GRK activator