Home Endocrinology & Hormones Aromatase

Aromatase

Aromatase Products

  • All (8)
  • Aromatase Inhibitors (8)
  • New Aromatase Products
Catalog No. Product Name Information Product Use Citations Product Validations
S1235 Letrozole Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.
eNeuro, 2024, 11(8)ENEURO.0332-24.2024
J Chromatogr B Analyt Technol Biomed Life Sci, 2024, 1238:124106
Mol Oncol, 2023, 10.1002/1878-0261.13541
S1188 Anastrozole Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.
Mol Oncol, 2023, 10.1002/1878-0261.13541
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
S1196 Exemestane Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
S9519 Fadrozole (CGS16949A) Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.
Epigenetics Chromatin, 2023, 16(1):2
Drug Test Anal, 2020, 10.1002/dta.2917
S3784 Obacunone (AI3-37934) Obacunone (AI3-37934, CCRIS 8657), a natural compound present in citrus fruits, has been demonstrated for various biological activities including anti-cancer and anti-inflammatory properties. It significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM; also a novel activator of Nrf2.
Int J Mol Sci, 2023, 24(14)11484
Cell Mol Biol Lett, 2022, 27(1):29
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
S2208 Formestane Formestane (CGP-32349, NSC 282175) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
S5158 alpha-Naphthoflavone Alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
S1235 Letrozole Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.
eNeuro, 2024, 11(8)ENEURO.0332-24.2024
J Chromatogr B Analyt Technol Biomed Life Sci, 2024, 1238:124106
Mol Oncol, 2023, 10.1002/1878-0261.13541
S1188 Anastrozole Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.
Mol Oncol, 2023, 10.1002/1878-0261.13541
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
S1196 Exemestane Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
Commun Biol, 2023, 6(1):695
S9519 Fadrozole (CGS16949A) Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.
Epigenetics Chromatin, 2023, 16(1):2
Drug Test Anal, 2020, 10.1002/dta.2917
S3784 Obacunone (AI3-37934) Obacunone (AI3-37934, CCRIS 8657), a natural compound present in citrus fruits, has been demonstrated for various biological activities including anti-cancer and anti-inflammatory properties. It significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM; also a novel activator of Nrf2.
Int J Mol Sci, 2023, 24(14)11484
Cell Mol Biol Lett, 2022, 27(1):29
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
S2208 Formestane Formestane (CGP-32349, NSC 282175) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
S5158 alpha-Naphthoflavone Alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.

Choose Selective Aromatase Inhibitors

AromataseSignaling Pathway

Aromatase信号通路图
Tags: aromatase inhibition | aromatase breast cancer | estrogen aromatase | aromatase inhibitors for men | aromatase inhibitors breast cancer | aromatase activity | aromatase deficiency | aromatase inhibitor therapy | aromatase inhibitors supplement | aromatase p450 | aromatase inhibitors for women | aromatase assay | aromatase inhibitors list | aromatase inhibitors mechanism | aromatase inhibitors drugs | aromatase pathway | aromatase inhibitor review