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1-Triacontanol

Cat.No.S5172

1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
1-Triacontanol Chemical Structure

Chemical Structure

Molecular Weight: 438.81

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S517201 4-Methylpyridine]10 mg/mL]true]Ethanol]1 mg/mL]false]DMSO]Insoluble]false Purity: 98%
98

Chemical Information, Storage & Stability

Molecular Weight 438.81 Formula

C30H62O

 Storage (From the date of receipt)
CAS No. 593-50-0 Download SDF Storage of Stock Solutions

Synonyms n-Triacontanol, Melissyl alcohol, Myricyl alcohol Smiles CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO

Solubility

In vitro
Batch:

4-Methylpyridine : 10 mg/mL

Ethanol : 1 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vivo
The area under concentration-time curve AUC0-6 h and AUC0-∞ for 1-Triacontanol (TA) at 60 mg/kg are 87.737±13.574 and 93.617±17.62, respectively. The mean residence time is 3.25 ± 0.17 h. In addition, the elimination half-lives (t1/2) are (2.37±1.23, 1.27±0.49, 2.07±0.93) h after single oral administration of 30, 60 and 120 mg/kg of TA. After oral administration, TA is extensively distributed in stomach and intestine. The majority of TA excrete via feces, and its accumulative excretion ratio during the period of 72 h is 26.68 ± 7.14%, but only 0.0023 ± 0.0015% and 0.0027 ± 0.0006% for urines and bile, respectively. The absolute bioavailability (F, %) of TA is about 2.0%. TA is regarded as a promising anti-cancer compound with less or no toxicity. Due to low bioavailability and undesirable half-life[1].
References

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