L-Hydroxyproline

Name: L-Hydroxyproline
Brand: Selleck Chemicals
SKU: S5820
Rating: 5 (1 reviews)

Synonyms: trans-4-Hydroxy-L-proline

Catalog No.S5820 Purity:99.64%

L-Hydroxyproline (trans-4-Hydroxy-L-proline) is a collagen-specific amino acid. It is used as a diagnostic marker of bone turnover and liver fibrosis.

L-Hydroxyproline Chemical Structure

CAS No. 51-35-4

Purity & Quality Control

Batch: S582001 Water]26 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.64%

99.64

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Biological Activity

Description	L-Hydroxyproline (trans-4-Hydroxy-L-proline) is a collagen-specific amino acid. It is used as a diagnostic marker of bone turnover and liver fibrosis.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05252962	Unknown status	Healthy	Rousselot BVBA\|BioTeSys GmbH	November 26 2021	Not Applicable
NCT04949607	Completed	Brain Injury Chronic\|Brain Injuries Traumatic	Centre for Neuro Skills\|University of Texas	July 28 2021	Not Applicable
NCT04097808	Completed	Bioavailability	Rousselot BVBA\|BioTeSys GmbH	September 20 2019	Not Applicable
NCT04065204	Unknown status	Pediatric Medulloblastoma	Xinhua Hospital Shanghai Jiao Tong University School of Medicine	June 1 2019	--

Chemical Information & Solubility

Molecular Weight	131.13	Formula	C₅H₉NO₃
CAS No.	51-35-4	SDF	--
Smiles	C1C(CNC1C(=O)O)O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 26 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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