Home Others Other chemical α-L-Rhamnose monohydrate For research use only.

α-L-Rhamnose monohydrate

Synonyms: 6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate

α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.

α-L-Rhamnose monohydrate Chemical Structure

α-L-Rhamnose monohydrate Chemical Structure

CAS No. 6155-35-7

Purity & Quality Control

Batch: S388701 DMSO]36 mg/mL]false]]]false]]]false Purity: 98%
98

α-L-Rhamnose monohydrate Related Products

Biological Activity

Description α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
In vitro
In vitro L-rhamnose in concentration up to 20 (32 resp.) mmol/l can not be considered as cytotoxic or cytostatic for the used in vitro tumor models[1].
Cell Research Cell lines HL-60 cells
Concentrations 0.125 mmol/l to 32 mmol/l
Incubation Time 48 h
Method At the beginning of the experiment, HL-60 cells are diluted to a concentration of 2x105/ml. Exponential growth of control cells is apparent during the observation interval. HL-60 cells are exposed to L-rhamnose or 2-deoxyglucose in final concentration from 0.125 mmol/l to 32 or 16 mmol/l, resp., in full cultivating medium.
In Vivo
In vivo L-rhamnose exerts a significant suppressive effect on tumour growth. Its optimal dose is estimated to be 3.64 g/kg/day[2].
Animal Research Animal Models NMRI female mice
Dosages 1, 3, or 5 g/kg/day
Administration i.p.

Chemical Information & Solubility

Molecular Weight 182.17 Formula

C6H12O5.H2O
CAS No. 6155-35-7 SDF Download α-L-Rhamnose monohydrate SDF
Smiles CC1C(C(C(C(O1)O)O)O)O.O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 36 mg/mL ( (197.61 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

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